An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo.
Fluharty BR, Biasini E, Stravalaci M, Sclip A, Diomede L, Balducci C, La Vitola P, Messa M, Colombo L, Forloni G, Borsello T, Gobbi M, Harris DA.
Fluharty BR, et al. Among authors: harris da.
J Biol Chem. 2013 Mar 15;288(11):7857-7866. doi: 10.1074/jbc.M112.423954. Epub 2013 Jan 28.
J Biol Chem. 2013.
PMID: 23362282
Free PMC article.