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Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML.
Brand M, Jiang B, Bauer S, Donovan KA, Liang Y, Wang ES, Nowak RP, Yuan JC, Zhang T, Kwiatkowski N, Müller AC, Fischer ES, Gray NS, Winter GE. Brand M, et al. Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9. doi: 10.1016/j.chembiol.2018.11.006. Epub 2018 Dec 27. Cell Chem Biol. 2019. PMID: 30595531 Free PMC article.
Stick it to E3s.
Brand M, Winter GE. Brand M, et al. Nat Chem Biol. 2019 Jul;15(7):655-656. doi: 10.1038/s41589-019-0312-8. Nat Chem Biol. 2019. PMID: 31209352 No abstract available.
Selective Mediator dependence of cell-type-specifying transcription.
Jaeger MG, Schwalb B, Mackowiak SD, Velychko T, Hanzl A, Imrichova H, Brand M, Agerer B, Chorn S, Nabet B, Ferguson FM, Müller AC, Bergthaler A, Gray NS, Bradner JE, Bock C, Hnisz D, Cramer P, Winter GE. Jaeger MG, et al. Among authors: brand m. Nat Genet. 2020 Jul;52(7):719-727. doi: 10.1038/s41588-020-0635-0. Epub 2020 Jun 1. Nat Genet. 2020. PMID: 32483291 Free PMC article.
Rational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Müller AC, Zuber J, Geyer M, Thomä NH, Kubicek S, Winter GE. Mayor-Ruiz C, et al. Among authors: brand m. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. Nat Chem Biol. 2020. PMID: 32747809 Free PMC article.
Publisher Correction: Rational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Müller AC, Zuber J, Geyer M, Thomä NH, Kubicek S, Winter GE. Mayor-Ruiz C, et al. Among authors: brand m. Nat Chem Biol. 2021 Mar;17(3):361. doi: 10.1038/s41589-021-00735-4. Nat Chem Biol. 2021. PMID: 33452497 No abstract available.
Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor Thr701 phosphorylation.
Gaviraghi M, Rabellino A, Andolfo A, Brand M, Brombin C, Bagnato P, De Feudis G, Raimondi A, Locatelli A, Tosoni D, Mazza D, Gianni L, Tonon G, Yarden Y, Tacchetti C, Daniele T. Gaviraghi M, et al. Among authors: brand m. Sci Rep. 2020 Oct 9;10(1):16906. doi: 10.1038/s41598-020-73835-1. Sci Rep. 2020. PMID: 33037285 Free PMC article.
1,582 results