Lin HC - Search Results

1

Biosynthesis of bioactive natural products from Basidiomycota.

Lin HC, Hewage RT, Lu YC, Chooi YH. Lin HC, et al. Org Biomol Chem. 2019 Jan 31;17(5):1027-1036. doi: 10.1039/c8ob02774a. Org Biomol Chem. 2019. PMID: 30608100 Review.

2

An Enzyme-Mediated Aza-Michael Addition Is Involved in the Biosynthesis of an Imidazoyl Hybrid Product of Conidiogenone B.

Hewage RT, Huang RJ, Lai SJ, Lien YC, Weng SH, Li D, Chen YJ, Wu SH, Chein RJ, Lin HC. Hewage RT, et al. Among authors: lin hc. Org Lett. 2021 Mar 5;23(5):1904-1909. doi: 10.1021/acs.orglett.1c00330. Epub 2021 Feb 11. Org Lett. 2021. PMID: 33570417

3

Biosynthesis of Complex Indole Alkaloids: Elucidation of the Concise Pathway of Okaramines.

Lai CY, Lo IW, Hewage RT, Chen YC, Chen CT, Lee CF, Lin S, Tang MC, Lin HC. Lai CY, et al. Among authors: lin s, lin hc. Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9478-9482. doi: 10.1002/anie.201705501. Epub 2017 Jul 6. Angew Chem Int Ed Engl. 2017. PMID: 28631282

4

Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids.

Lin HC, Chiou G, Chooi YH, McMahon TC, Xu W, Garg NK, Tang Y. Lin HC, et al. Angew Chem Int Ed Engl. 2015 Mar 2;54(10):3004-7. doi: 10.1002/anie.201411297. Epub 2015 Jan 8. Angew Chem Int Ed Engl. 2015. PMID: 25571861 Free PMC article.

5

Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System.

Mao XM, Zhan ZJ, Grayson MN, Tang MC, Xu W, Li YQ, Yin WB, Lin HC, Chooi YH, Houk KN, Tang Y. Mao XM, et al. Among authors: lin hc. J Am Chem Soc. 2015 Sep 23;137(37):11904-7. doi: 10.1021/jacs.5b07816. Epub 2015 Sep 10. J Am Chem Soc. 2015. PMID: 26340065 Free PMC article.

6

Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway.

Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y. Lin HC, et al. J Am Chem Soc. 2014 Mar 19;136(11):4426-36. doi: 10.1021/ja500881e. Epub 2014 Mar 11. J Am Chem Soc. 2014. PMID: 24568283 Free PMC article.

7

Fungal polyketide synthase product chain-length control by partnering thiohydrolase.

Zabala AO, Chooi YH, Choi MS, Lin HC, Tang Y. Zabala AO, et al. Among authors: lin hc. ACS Chem Biol. 2014 Jul 18;9(7):1576-86. doi: 10.1021/cb500284t. Epub 2014 May 29. ACS Chem Biol. 2014. PMID: 24845309 Free PMC article.

8

The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene.

Lin HC, Chooi YH, Dhingra S, Xu W, Calvo AM, Tang Y. Lin HC, et al. J Am Chem Soc. 2013 Mar 27;135(12):4616-9. doi: 10.1021/ja312503y. Epub 2013 Mar 19. J Am Chem Soc. 2013. PMID: 23488861 Free PMC article.

9

Biosynthesis of Piperazine-Derived Diazabicyclic Alkaloids Involves a Nonribosomal Peptide Synthetase and Subsequent Tailoring by a Multifunctional Cytochrome P450 Enzyme.

Pham MT, Chen SR, Liang SY, Cheng YB, Lin HC. Pham MT, et al. Among authors: lin hc. Org Lett. 2022 Jun 10;24(22):4064-4069. doi: 10.1021/acs.orglett.2c01516. Epub 2022 May 26. Org Lett. 2022. PMID: 35617650

10

Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis.

Chen KL, Lai CY, Pham MT, Chein RJ, Tang Y, Lin HC. Chen KL, et al. Among authors: lin hc. Org Lett. 2020 Apr 17;22(8):3302-3306. doi: 10.1021/acs.orglett.0c01132. Epub 2020 Apr 3. Org Lett. 2020. PMID: 32243182 Free PMC article.

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