Meanwell NA - Search Results

1

Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors.

Yeung KS, Beno BR, Mosure K, Zhu J, Grant-Young KA, Parcella K, Anjanappa P, Bora RO, Selvakumar K, Wang YK, Fang H, Krause R, Rigat K, Liu M, Lemm J, Sheriff S, Witmer M, Tredup J, Jardel A, Kish K, Parker D, Haskell R, Santone K, Meanwell NA, Soars MG, Roberts SB, Kadow JF. Yeung KS, et al. Among authors: meanwell na. ACS Med Chem Lett. 2018 Nov 5;9(12):1217-1222. doi: 10.1021/acsmedchemlett.8b00379. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613329 Free PMC article.

2

Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility.

Meanwell NA, Dennis RD, Roth HR, Rosenfeld MJ, Smith EC, Wright JJ, Buchanan JO, Brassard CL, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. J Med Chem. 1992 Jul 10;35(14):2688-96. doi: 10.1021/jm00092a020. J Med Chem. 1992. PMID: 1321911

3

Structure-activity relationship studies of a bisbenzimidazole-based, Zn(2+)-dependent inhibitor of HCV NS3 serine protease.

Yeung KS, Meanwell NA, Qiu Z, Hernandez D, Zhang S, McPhee F, Weinheimer S, Clark JM, Janc JW. Yeung KS, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2355-9. doi: 10.1016/s0960-894x(01)00457-7. Bioorg Med Chem Lett. 2001. PMID: 11527730

4

A strategy for the synthesis of aryl alpha-ketoamides based upon the acylation of anions derived from cyanomethylamines followed by oxidative cleavage.

Yang Z, Zhang Z, Meanwell NA, Kadow JF, Wang T. Yang Z, et al. Among authors: meanwell na. Org Lett. 2002 Apr 4;4(7):1103-5. doi: 10.1021/ol010297l. Org Lett. 2002. PMID: 11922793

5

A general method for the preparation of 4- and 6-azaindoles.

Zhang Z, Yang Z, Meanwell NA, Kadow JF, Wang T. Zhang Z, et al. Among authors: meanwell na. J Org Chem. 2002 Apr 5;67(7):2345-7. doi: 10.1021/jo0111614. J Org Chem. 2002. PMID: 11925251

6

An effective procedure for the acylation of azaindoles at C-3.

Zhang Z, Yang Z, Wong H, Zhu J, Meanwell NA, Kadow JF, Wang T. Zhang Z, et al. Among authors: meanwell na. J Org Chem. 2002 Aug 23;67(17):6226-7. doi: 10.1021/jo020135i. J Org Chem. 2002. PMID: 12182666

7

Highly potent non-peptidic inhibitors of the HCV NS3/NS4A serine protease.

Sperandio D, Gangloff AR, Litvak J, Goldsmith R, Hataye JM, Wang VR, Shelton EJ, Elrod K, Janc JW, Clark JM, Rice K, Weinheimer S, Yeung KS, Meanwell NA, Hernandez D, Staab AJ, Venables BL, Spencer JR. Sperandio D, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3129-33. doi: 10.1016/s0960-894x(02)00680-7. Bioorg Med Chem Lett. 2002. PMID: 12372517

8

Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine.

Yu KL, Torri AF, Luo G, Cianci C, Grant-Young K, Danetz S, Tiley L, Krystal M, Meanwell NA. Yu KL, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3379-82. doi: 10.1016/s0960-894x(02)00761-8. Bioorg Med Chem Lett. 2002. PMID: 12419365

9

Fundamental structure-activity relationships associated with a new structural class of respiratory syncytial virus inhibitor.

Yu KL, Zhang Y, Civiello RL, Kadow KF, Cianci C, Krystal M, Meanwell NA. Yu KL, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2141-4. doi: 10.1016/s0960-894x(03)00383-4. Bioorg Med Chem Lett. 2003. PMID: 12798322

10

Inhibitors of the entry of HIV into host cells.

Meanwell NA, Kadow JF. Meanwell NA, et al. Curr Opin Drug Discov Devel. 2003 Jul;6(4):451-61. Curr Opin Drug Discov Devel. 2003. PMID: 12951808 Review.

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