Liu KH - Search Results

1

Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.

Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: liu kh. J Med Chem. 2019 Jan 24;62(2):575-588. doi: 10.1021/acs.jmedchem.8b01168. Epub 2019 Jan 9. J Med Chem. 2019. PMID: 30623649

2

In vitro metabolism and transport of the new dipeptidyl peptidase 4 inhibitors, KR66222 and KR66223.

Ahn HJ, Kim KB, Liu KH, Shin JG, Ahn JH, Kim MS, Bae MA, Song IS. Ahn HJ, et al. Among authors: liu kh. Xenobiotica. 2011 Jun;41(6):445-55. doi: 10.3109/00498254.2011.552649. Epub 2011 Feb 22. Xenobiotica. 2011. PMID: 21341986

3

In vitro metabolism of obovatol and its effect on cytochrome P450 enzyme activities in human liver microsomes.

Joo J, Lee D, Wu Z, Shin JH, Lee HS, Kwon BM, Huh TL, Kim YW, Lee SJ, Kim TW, Lee T, Liu KH. Joo J, et al. Among authors: liu kh. Biopharm Drug Dispos. 2013 May;34(4):195-202. doi: 10.1002/bdd.1837. Epub 2013 Mar 26. Biopharm Drug Dispos. 2013. PMID: 23446989

4

Potential of decursin to inhibit the human cytochrome P450 2J2 isoform.

Lee B, Wu Z, Sung SH, Lee T, Song KS, Lee MY, Liu KH. Lee B, et al. Among authors: liu kh. Food Chem Toxicol. 2014 Aug;70:94-9. doi: 10.1016/j.fct.2014.04.020. Epub 2014 Apr 29. Food Chem Toxicol. 2014. PMID: 24788058

5

Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer.

Sim J, Nam W, Lee D, Lee S, O H, Joo J, Liu KH, Han JY, Ki SH, Jeong TC, Lee T, Lee S. Sim J, et al. Among authors: liu kh. Arch Pharm Res. 2015;38(5):725-33. doi: 10.1007/s12272-014-0443-0. Epub 2014 Jul 23. Arch Pharm Res. 2015. PMID: 25052955

6

Screening of six UGT enzyme activities in human liver microsomes using liquid chromatography/triple quadrupole mass spectrometry.

Joo J, Lee B, Lee T, Liu KH. Joo J, et al. Among authors: liu kh. Rapid Commun Mass Spectrom. 2014 Nov 30;28(22):2405-14. doi: 10.1002/rcm.7030. Rapid Commun Mass Spectrom. 2014. PMID: 25303469

7

In vitro metabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s.

Joo J, Wu Z, Lee B, Shon JC, Lee T, Lee IK, Sim T, Kim KH, Kim ND, Kim SH, Liu KH. Joo J, et al. Among authors: liu kh. Biopharm Drug Dispos. 2015 Apr;36(3):163-73. doi: 10.1002/bdd.1929. Epub 2015 Jan 24. Biopharm Drug Dispos. 2015. PMID: 25451157

8

Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.

Lee B, Ji HK, Lee T, Liu KH. Lee B, et al. Among authors: liu kh. Drug Metab Dispos. 2015 Jul;43(7):1137-46. doi: 10.1124/dmd.114.063016. Epub 2015 Apr 22. Drug Metab Dispos. 2015. PMID: 25904760

9

In vitro characterization of 4'-(p-toluenesulfonylamide)-4-hydroxychalcone using human liver microsomes and recombinant cytochrome P450s.

Lee B, Wu Z, Lee T, Tan XF, Park KH, Liu KH. Lee B, et al. Among authors: liu kh. Xenobiotica. 2016;46(4):350-6. doi: 10.3109/00498254.2015.1081306. Epub 2015 Sep 2. Xenobiotica. 2016. PMID: 26330107

10

Solid-Phase Synthesis of 1,3,7,8-Tetrasubstituted Xanthine Derivatives on Traceless Solid Support.

Lee D, Lee S, Liu KH, Bae JS, Baek DJ, Lee T. Lee D, et al. Among authors: liu kh. ACS Comb Sci. 2016 Jan 11;18(1):70-4. doi: 10.1021/acscombsci.5b00148. Epub 2015 Dec 14. ACS Comb Sci. 2016. PMID: 26616892

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