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Page 1
Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: yoo ek. J Med Chem. 2019 Jan 24;62(2):575-588. doi: 10.1021/acs.jmedchem.8b01168. Epub 2019 Jan 9. J Med Chem. 2019. PMID: 30623649
Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Kim J, Woo SY, Im CY, Yoo EK, Lee S, Kim HJ, Hwang HJ, Cho JH, Lee WS, Yoon H, Kim S, Kwon OB, Hwang H, Kim KH, Jeon JH, Singh TD, Kim SW, Hwang SY, Choi HS, Lee IK, Kim SH, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: yoo ek. J Med Chem. 2016 Nov 23;59(22):10209-10227. doi: 10.1021/acs.jmedchem.6b01204. Epub 2016 Nov 9. J Med Chem. 2016. PMID: 27805390
Correction to Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: yoo ek. J Med Chem. 2019 Mar 14;62(5):2849. doi: 10.1021/acs.jmedchem.9b00249. Epub 2019 Feb 27. J Med Chem. 2019. PMID: 30811938 No abstract available.
Identification of Selective ERRγ Inverse Agonists.
Kim J, Im CY, Yoo EK, Ma MJ, Kim SB, Hong E, Chin J, Hwang H, Lee S, Kim ND, Jeon JH, Lee IK, Jeon YH, Choi HS, Kim SH, Cho SJ. Kim J, et al. Among authors: yoo ek. Molecules. 2016 Jan 12;21(1):80. doi: 10.3390/molecules21010080. Molecules. 2016. PMID: 26771593 Free PMC article.
Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
Kim J, Song J, Ji HD, Yoo EK, Lee JE, Lee SB, Oh JM, Lee S, Hwang JS, Yoon H, Kim DS, Lee SJ, Jeong M, Lee S, Kim KH, Choi HS, Lee SW, Park KG, Lee IK, Kim SH, Hwang H, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: yoo ek. J Med Chem. 2019 Feb 28;62(4):1837-1858. doi: 10.1021/acs.jmedchem.8b01296. Epub 2019 Feb 4. J Med Chem. 2019. PMID: 30657313
Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.
Min BK, Park S, Kang HJ, Kim DW, Ham HJ, Ha CM, Choi BJ, Lee JY, Oh CJ, Yoo EK, Kim HE, Kim BG, Jeon JH, Hyeon DY, Hwang D, Kim YH, Lee CH, Lee T, Kim JW, Choi YK, Park KG, Chawla A, Lee J, Harris RA, Lee IK. Min BK, et al. Among authors: yoo ek. Front Immunol. 2019 May 7;10:944. doi: 10.3389/fimmu.2019.00944. eCollection 2019. Front Immunol. 2019. PMID: 31134063 Free PMC article.
42 results