Zhang JK - Search Results

1

Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles.

Dong XW, Zhang JK, Xu L, Che JX, Cheng G, Hu XB, Sheng L, Gao AH, Li J, Liu T, Hu YZ, Zhou YB. Dong XW, et al. Among authors: zhang jk. Eur J Med Chem. 2019 Feb 15;164:602-614. doi: 10.1016/j.ejmech.2018.12.064. Epub 2018 Dec 26. Eur J Med Chem. 2019. PMID: 30639896

2

Identification of novel piperazinylquinoxaline derivatives as potent phosphoinositide 3-kinase (PI3K) inhibitors.

Wu P, Su Y, Guan X, Liu X, Zhang J, Dong X, Huang W, Hu Y. Wu P, et al. PLoS One. 2012;7(8):e43171. doi: 10.1371/journal.pone.0043171. Epub 2012 Aug 14. PLoS One. 2012. PMID: 22905224 Free PMC article.

3

Clinical and marketed proteasome inhibitors for cancer treatment.

Zhang J, Wu P, Hu Y. Zhang J, et al. Curr Med Chem. 2013;20(20):2537-51. doi: 10.2174/09298673113209990122. Curr Med Chem. 2013. PMID: 23531219 Review.

4

Design, synthesis and biological evaluation of novel non-peptide boronic acid derivatives as proteasome inhibitors.

Zhang J, Shen L, Wang J, Luo P, Hu Y. Zhang J, et al. Med Chem. 2014;10(1):38-45. doi: 10.2174/15734064113099990006. Med Chem. 2014. PMID: 23676009

5

Design, synthesis and biological evaluation of peptidyl epoxyketone proteasome inhibitors composed of β-amino acids.

Zhang J, Han M, Ma X, Xu L, Cao J, Zhou Y, Li J, Liu T, Hu Y. Zhang J, et al. Chem Biol Drug Des. 2014 Nov;84(5):497-504. doi: 10.1111/cbdd.12342. Epub 2014 Jun 3. Chem Biol Drug Des. 2014. PMID: 24751157

6

Design, synthesis and biological evaluation of novel tripeptidyl epoxyketone derivatives constructed from β-amino acid as proteasome inhibitors.

Zhang J, Cao J, Xu L, Zhou Y, Liu T, Li J, Hu Y. Zhang J, et al. Bioorg Med Chem. 2014 Jun 1;22(11):2955-65. doi: 10.1016/j.bmc.2014.04.011. Epub 2014 Apr 13. Bioorg Med Chem. 2014. PMID: 24767818

7

Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors.

Zhang J, Gao L, Xi J, Sheng L, Zhao Y, Xu L, Shao Y, Liu S, Zhuang R, Zhou Y, Li J. Zhang J, et al. Bioorg Med Chem. 2016 Dec 1;24(23):6206-6214. doi: 10.1016/j.bmc.2016.10.002. Epub 2016 Oct 6. Bioorg Med Chem. 2016. PMID: 27765408

8

Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors.

Zhuang R, Gao L, Lv X, Xi J, Sheng L, Zhao Y, He R, Hu X, Shao Y, Pan X, Liu S, Huang W, Zhou Y, Li J, Zhang J. Zhuang R, et al. Eur J Med Chem. 2017 Jan 27;126:1056-1070. doi: 10.1016/j.ejmech.2016.12.034. Epub 2016 Dec 18. Eur J Med Chem. 2017. PMID: 28027531

9

Discovery of a series of N-(5-(quinolin-6-yl)pyridin-3-yl)benzenesulfonamides as PI3K/mTOR dual inhibitors.

Zhang J, Lv X, Ma X, Hu Y. Zhang J, et al. Eur J Med Chem. 2017 Feb 15;127:509-520. doi: 10.1016/j.ejmech.2017.01.016. Epub 2017 Jan 11. Eur J Med Chem. 2017. PMID: 28109945

10

Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.

Zhao Y, Zhang J, Zhuang R, He R, Xi J, Pan X, Shao Y, Pan J, Sun J, Cai Z, Liu S, Huang W, Lv X. Zhao Y, et al. Bioorg Med Chem. 2017 Jun 15;25(12):3195-3205. doi: 10.1016/j.bmc.2017.04.003. Epub 2017 Apr 5. Bioorg Med Chem. 2017. PMID: 28412159

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