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Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
Vögerl K, Ong N, Senger J, Herp D, Schmidtkunz K, Marek M, Müller M, Bartel K, Shaik TB, Porter NJ, Robaa D, Christianson DW, Romier C, Sippl W, Jung M, Bracher F. Vögerl K, et al. Among authors: porter nj. J Med Chem. 2019 Feb 14;62(3):1138-1166. doi: 10.1021/acs.jmedchem.8b01090. Epub 2019 Feb 1. J Med Chem. 2019. PMID: 30645113 Free PMC article.
Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
Porter NJ, Mahendran A, Breslow R, Christianson DW. Porter NJ, et al. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13459-13464. doi: 10.1073/pnas.1718823114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203661 Free PMC article.
33 results