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Epigenetic therapy for ovarian cancer: promise and progress.
Moufarrij S, Dandapani M, Arthofer E, Gomez S, Srivastava A, Lopez-Acevedo M, Villagra A, Chiappinelli KB. Moufarrij S, et al. Among authors: chiappinelli kb. Clin Epigenetics. 2019 Jan 15;11(1):7. doi: 10.1186/s13148-018-0602-0. Clin Epigenetics. 2019. PMID: 30646939 Free PMC article. Review.
Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer.
Topper MJ, Vaz M, Chiappinelli KB, DeStefano Shields CE, Niknafs N, Yen RC, Wenzel A, Hicks J, Ballew M, Stone M, Tran PT, Zahnow CA, Hellmann MD, Anagnostou V, Strissel PL, Strick R, Velculescu VE, Baylin SB. Topper MJ, et al. Among authors: chiappinelli kb. Cell. 2017 Nov 30;171(6):1284-1300.e21. doi: 10.1016/j.cell.2017.10.022. Cell. 2017. PMID: 29195073 Free PMC article.
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, Strick R, Strissel PL, Baylin SB, Zahnow CA. Stone ML, et al. Among authors: chiappinelli kb. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10981-E10990. doi: 10.1073/pnas.1712514114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203668 Free PMC article.
Combining epigenetic and immune therapy to overcome cancer resistance.
Gomez S, Tabernacki T, Kobyra J, Roberts P, Chiappinelli KB. Gomez S, et al. Among authors: chiappinelli kb. Semin Cancer Biol. 2020 Oct;65:99-113. doi: 10.1016/j.semcancer.2019.12.019. Epub 2019 Dec 23. Semin Cancer Biol. 2020. PMID: 31877341 Free PMC article. Review.
HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer.
Banik D, Noonepalle S, Hadley M, Palmer E, Gracia-Hernandez M, Zevallos-Delgado C, Manhas N, Simonyan H, Young CN, Popratiloff A, Chiappinelli KB, Fernandes R, Sotomayor EM, Villagra A. Banik D, et al. Among authors: chiappinelli kb. Cancer Res. 2020 Sep 1;80(17):3649-3662. doi: 10.1158/0008-5472.CAN-19-3738. Epub 2020 Jun 30. Cancer Res. 2020. PMID: 32605998 Free PMC article.
Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner.
McDonald JI, Diab N, Arthofer E, Hadley M, Kanholm T, Rentia U, Gomez S, Yu A, Grundy EE, Cox O, Topper MJ, Xing X, Strissel PL, Strick R, Wang T, Baylin SB, Chiappinelli KB. McDonald JI, et al. Among authors: chiappinelli kb. Cancer Res. 2021 Oct 15;81(20):5176-5189. doi: 10.1158/0008-5472.CAN-20-4243. Epub 2021 Aug 25. Cancer Res. 2021. PMID: 34433584 Free PMC article.
Editorial: Genetic and Epigenetic Control of Immune Responses.
Noonepalle SKR, Karabon L, Chiappinelli KB, Villagra A. Noonepalle SKR, et al. Among authors: chiappinelli kb. Front Immunol. 2021 Oct 5;12:775101. doi: 10.3389/fimmu.2021.775101. eCollection 2021. Front Immunol. 2021. PMID: 34675944 Free PMC article. No abstract available.
Author Correction: Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer.
Moufarrij S, Srivastava A, Gomez S, Hadley M, Palmer E, Austin PT, Chisholm S, Diab N, Roche K, Yu A, Li J, Zhu W, Lopez-Acevedo M, Villagra A, Chiappinelli KB. Moufarrij S, et al. Among authors: chiappinelli kb. Sci Rep. 2021 Dec 20;11(1):24423. doi: 10.1038/s41598-021-04066-1. Sci Rep. 2021. PMID: 34931014 Free PMC article. No abstract available.
48 results