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Page 1
P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus.
Faliti CE, Gualtierotti R, Rottoli E, Gerosa M, Perruzza L, Romagnani A, Pellegrini G, De Ponte Conti B, Rossi RL, Idzko M, Mazza EMC, Bicciato S, Traggiai E, Meroni PL, Grassi F. Faliti CE, et al. J Exp Med. 2019 Feb 4;216(2):317-336. doi: 10.1084/jem.20171976. Epub 2019 Jan 17. J Exp Med. 2019. PMID: 30655308 Free PMC article.
ATP-gated ionotropic P2X7 receptor controls follicular T helper cell numbers in Peyer's patches to promote host-microbiota mutualism.
Proietti M, Cornacchione V, Rezzonico Jost T, Romagnani A, Faliti CE, Perruzza L, Rigoni R, Radaelli E, Caprioli F, Preziuso S, Brannetti B, Thelen M, McCoy KD, Slack E, Traggiai E, Grassi F. Proietti M, et al. Among authors: faliti ce. Immunity. 2014 Nov 20;41(5):789-801. doi: 10.1016/j.immuni.2014.10.010. Epub 2014 Nov 13. Immunity. 2014. PMID: 25464855 Free article.
T Follicular Helper Cells Promote a Beneficial Gut Ecosystem for Host Metabolic Homeostasis by Sensing Microbiota-Derived Extracellular ATP.
Perruzza L, Gargari G, Proietti M, Fosso B, D'Erchia AM, Faliti CE, Rezzonico-Jost T, Scribano D, Mauri L, Colombo D, Pellegrini G, Moregola A, Mooser C, Pesole G, Nicoletti M, Norata GD, Geuking MB, McCoy KD, Guglielmetti S, Grassi F. Perruzza L, et al. Among authors: faliti ce. Cell Rep. 2017 Mar 14;18(11):2566-2575. doi: 10.1016/j.celrep.2017.02.061. Cell Rep. 2017. PMID: 28297661 Free PMC article.
Dependence of immunoglobulin class switch recombination in B cells on vesicular release of ATP and CD73 ectonucleotidase activity.
Schena F, Volpi S, Faliti CE, Penco F, Santi S, Proietti M, Schenk U, Damonte G, Salis A, Bellotti M, Fais F, Tenca C, Gattorno M, Eibel H, Rizzi M, Warnatz K, Idzko M, Ayata CK, Rakhmanov M, Galli T, Martini A, Canossa M, Grassi F, Traggiai E. Schena F, et al. Among authors: faliti ce. Cell Rep. 2013 Jun 27;3(6):1824-31. doi: 10.1016/j.celrep.2013.05.022. Epub 2013 Jun 13. Cell Rep. 2013. PMID: 23770243 Free article.
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection.
Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. Dan JM, et al. Among authors: faliti ce. Science. 2021 Feb 5;371(6529):eabf4063. doi: 10.1126/science.abf4063. Epub 2021 Jan 6. Science. 2021. PMID: 33408181 Free PMC article.
Immunological memory to SARS-CoV-2 assessed for up to eight months after infection.
Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. Dan JM, et al. Among authors: faliti ce. bioRxiv [Preprint]. 2020 Dec 18:2020.11.15.383323. doi: 10.1101/2020.11.15.383323. bioRxiv. 2020. Update in: Science. 2021 Feb 5;371(6529):eabf4063. doi: 10.1126/science.abf4063 PMID: 33442687 Free PMC article. Updated. Preprint.
Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.
Faliti CE, Mesina M, Choi J, Bélanger S, Marshall MA, Tipton CM, Hicks S, Chappa P, Cardenas MA, Abdel-Hakeem M, Thinnes TC, Cottrell C, Scharer CD, Schief WR, Nemazee D, Woodruff MC, Lindner JM, Sanz I, Crotty S. Faliti CE, et al. Immunity. 2024 Nov 26:S1074-7613(24)00521-1. doi: 10.1016/j.immuni.2024.11.006. Online ahead of print. Immunity. 2024. PMID: 39612915
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Faliti CE, Van TTP, Anam FA, Cheedarla N, Williams ME, Mishra AK, Usman SY, Woodruff MC, Kraker G, Runnstrom MC, Kyu S, Sanz D, Ahmed H, Ghimire M, Morrison-Porter A, Quehl H, Haddad NS, Chen W, Cheedarla S, Neish AS, Roback JD, Antia R, Hom J, Tipton CM, Lindner JM, Ghosn E, Khurana S, Scharer CD, Khosroshahi A, Lee FE, Sanz I. Faliti CE, et al. Nat Immunol. 2024 Nov 12. doi: 10.1038/s41590-024-02010-9. Online ahead of print. Nat Immunol. 2024. PMID: 39533072
Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.
Runnstrom MC, Lamothe PA, Faliti CE, Cheedarla N, Moreno A, Suthar MS, Nahata R, Ravindran M, Haddad NS, Morrison-Porter A, Quehl H, Ramonell RP, Woodruff M, Anam F, Zhang R, Swenson C, Polito C, Neveu W, Patel R, Smirnova N, Nguyen DC, Kim C, Hentenaar I, Kyu S, Usman S, Ngo T, Guo Z, Wu H, Daiss JL, Park J, Manning KE, Wali B, Ellis ML, Sharma S, Holguin F, Cheedarla S, Neish AS, Roback JD, Sanz I, Eun-Hyung Lee F. Runnstrom MC, et al. Among authors: faliti ce. J Allergy Clin Immunol. 2024 Aug;154(2):435-446. doi: 10.1016/j.jaci.2024.03.029. Epub 2024 Jun 13. J Allergy Clin Immunol. 2024. PMID: 38878020 Free PMC article.
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