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Curcumin Pharmacokinetic and Pharmacodynamic Evidences in Streptozotocin-Diabetic Rats Support the Antidiabetic Activity to Be via Metabolite(s).
Gutierres VO, Campos ML, Arcaro CA, Assis RP, Baldan-Cimatti HM, Peccinini RG, Paula-Gomes S, Kettelhut IC, Baviera AM, Brunetti IL. Gutierres VO, et al. Evid Based Complement Alternat Med. 2015;2015:678218. doi: 10.1155/2015/678218. Epub 2015 May 3. Evid Based Complement Alternat Med. 2015. PMID: 26064170 Free PMC article.
Insulin treatment reverses the increase in atrogin-1 expression in atrophied skeletal muscles of diabetic rats with acute joint inflammation.
Pinheiro-Dardis CM, Gutierres VO, Assis RP, Peviani SM, Delfino GB, Durigan JLQ, Salvini TF, Baviera AM, Brunetti IL. Pinheiro-Dardis CM, et al. Among authors: gutierres vo. Ther Clin Risk Manag. 2018 Feb 14;14:275-286. doi: 10.2147/TCRM.S142948. eCollection 2018. Ther Clin Risk Manag. 2018. PMID: 29497304 Free PMC article.