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Page 1
Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance.
Okada K, Araki M, Sakashita T, Ma B, Kanada R, Yanagitani N, Horiike A, Koike S, Oh-Hara T, Watanabe K, Tamai K, Maemondo M, Nishio M, Ishikawa T, Okuno Y, Fujita N, Katayama R. Okada K, et al. Among authors: tamai k. EBioMedicine. 2019 Mar;41:105-119. doi: 10.1016/j.ebiom.2019.01.019. Epub 2019 Jan 17. EBioMedicine. 2019. PMID: 30662002 Free PMC article.
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.
Mizuta H, Okada K, Araki M, Adachi J, Takemoto A, Kutkowska J, Maruyama K, Yanagitani N, Oh-Hara T, Watanabe K, Tamai K, Friboulet L, Katayama K, Ma B, Sasakura Y, Sagae Y, Kukimoto-Niino M, Shirouzu M, Takagi S, Simizu S, Nishio M, Okuno Y, Fujita N, Katayama R. Mizuta H, et al. Among authors: tamai k. Nat Commun. 2021 Feb 24;12(1):1261. doi: 10.1038/s41467-021-21396-w. Nat Commun. 2021. PMID: 33627640 Free PMC article.
Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
Saijoh S, Nakamura-Shima M, Shibuya-Takahashi R, Ito R, Sugawara A, Yamazaki T, Imai T, Asada Y, Matsuura K, Iwai W, Wakui Y, Abue M, Kawamura S, Katayose Y, Fujimori H, Mochizuki M, Yasuda J, Yamaguchi K, Sugamura K, Satoh K, Katori Y, Tamai K. Saijoh S, et al. Among authors: tamai k. Biochem Biophys Res Commun. 2021 Jan 22;537:132-139. doi: 10.1016/j.bbrc.2020.11.022. Epub 2021 Jan 4. Biochem Biophys Res Commun. 2021. PMID: 33412384
CD271 is a negative prognostic factor and essential for cell proliferation in lung squamous cell carcinoma.
Mochizuki M, Nakamura M, Sibuya R, Okazaki T, Abe J, Nakagawa T, Takahashi S, Yamazaki T, Imai T, Takano A, Ito H, Yokose T, Miyagi Y, Daigo Y, Sato I, Satoh K, Sugamura K, Yamaguchi K, Tamai K. Mochizuki M, et al. Among authors: tamai k. Lab Invest. 2019 Sep;99(9):1349-1362. doi: 10.1038/s41374-019-0246-5. Epub 2019 Apr 24. Lab Invest. 2019. PMID: 31019292 Free article.
Novel activating KRAS mutation candidates in lung adenocarcinoma.
Abe J, Tanuma N, Nomura M, Ito S, Kasugai I, Sato I, Tamai K, Mochizuki M, Yamaguchi K, Shima H, Okada Y, Yasuda J. Abe J, et al. Among authors: tamai k. Biochem Biophys Res Commun. 2020 Feb 12;522(3):690-696. doi: 10.1016/j.bbrc.2019.11.151. Epub 2019 Nov 28. Biochem Biophys Res Commun. 2020. PMID: 31787238
BEX2 is required for maintaining dormant cancer stem cell in hepatocellular carcinoma.
Fukushi D, Shibuya-Takahashi R, Mochizuki M, Fujimori H, Kogure T, Sugai T, Iwai W, Wakui Y, Abue M, Murakami K, Nakamura Y, Yasuda J, Yamaguchi K, Sugamura K, Shibata C, Katayose Y, Satoh K, Tamai K. Fukushi D, et al. Among authors: tamai k. Cancer Sci. 2021 Nov;112(11):4580-4592. doi: 10.1111/cas.15115. Epub 2021 Sep 4. Cancer Sci. 2021. PMID: 34424582 Free PMC article.
1,032 results