Human macrophage cathepsin B-mediated C-terminal cleavage of apolipoprotein A-I at Ser228 severely impairs antiatherogenic capacity.
Dinnes DL, White MY, Kockx M, Traini M, Hsieh V, Kim MJ, Hou L, Jessup W, Rye KA, Thaysen-Andersen M, Cordwell SJ, Kritharides L.
Dinnes DL, et al. Among authors: kritharides l.
FASEB J. 2016 Dec;30(12):4239-4255. doi: 10.1096/fj.201600508R. Epub 2016 Sep 14.
FASEB J. 2016.
PMID: 27630170
Cleavage at Ser(228) is a novel, functionally important post-translational modification of apoA-I mediated by HMDMs that limits the antiatherogenic properties of apoA-I.-Dinnes, D. L. M., White, M. Y., Kockx, M., Traini, M., Hsieh, V., Kim, M.-J., Hou, L., Jessup, W …
Cleavage at Ser(228) is a novel, functionally important post-translational modification of apoA-I mediated by HMDMs that limits the antiathe …