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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT. Cohen F, et al. ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5. ChemMedChem. 2019. PMID: 31283109
Characterization of mavacamten pharmacokinetics in patients with hypertrophic cardiomyopathy to inform dose titration.
Chang P, Perera V, Salinger DH, Merali S, Thanneer N, Back H, Seroogy JD, Gretler DD, Sehnert AJ, Palmisano M, Roy A. Chang P, et al. Among authors: seroogy jd. CPT Pharmacometrics Syst Pharmacol. 2024 Sep;13(9):1462-1475. doi: 10.1002/psp4.13197. Epub 2024 Aug 13. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39136278 Free PMC article.
12 results