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Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.
Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A. Nokin MJ, et al. Among authors: bellier j. Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7. Breast Cancer Res. 2019. PMID: 30674353 Free PMC article.
Stromal Modulators of TGF-β in Cancer.
Costanza B, Umelo IA, Bellier J, Castronovo V, Turtoi A. Costanza B, et al. Among authors: bellier j. J Clin Med. 2017 Jan 6;6(1):7. doi: 10.3390/jcm6010007. J Clin Med. 2017. PMID: 28067804 Free PMC article. Review.
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.
Chiavarina B, Nokin MJ, Bellier J, Durieux F, Bletard N, Sherer F, Lovinfosse P, Peulen O, Verset L, Dehon R, Demetter P, Turtoi A, Uchida K, Goldman S, Hustinx R, Delvenne P, Castronovo V, Bellahcène A. Chiavarina B, et al. Among authors: bellier j. Int J Mol Sci. 2017 Jan 21;18(1):213. doi: 10.3390/ijms18010213. Int J Mol Sci. 2017. PMID: 28117708 Free PMC article.
Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.
Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A. Blomme A, et al. Among authors: bellier j. Oncogene. 2018 Mar;37(9):1237-1250. doi: 10.1038/s41388-017-0018-x. Epub 2017 Dec 15. Oncogene. 2018. PMID: 29242606
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness.
Rademaker G, Hennequière V, Brohée L, Nokin MJ, Lovinfosse P, Durieux F, Gofflot S, Bellier J, Costanza B, Herfs M, Peiffer R, Bettendorff L, Deroanne C, Thiry M, Delvenne P, Hustinx R, Bellahcène A, Castronovo V, Peulen O. Rademaker G, et al. Among authors: bellier j. Oncogene. 2018 Aug;37(32):4398-4412. doi: 10.1038/s41388-018-0287-z. Epub 2018 May 3. Oncogene. 2018. PMID: 29720728 Free PMC article.
Transforming growth factor beta-induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration.
Costanza B, Rademaker G, Tiamiou A, De Tullio P, Leenders J, Blomme A, Bellier J, Bianchi E, Turtoi A, Delvenne P, Bellahcène A, Peulen O, Castronovo V. Costanza B, et al. Among authors: bellier j. Int J Cancer. 2019 Sep 15;145(6):1570-1584. doi: 10.1002/ijc.32247. Epub 2019 Mar 28. Int J Cancer. 2019. PMID: 30834519 Free article.
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab.
Bellier J, Nokin MJ, Caprasse M, Tiamiou A, Blomme A, Scheijen JL, Koopmansch B, MacKay GM, Chiavarina B, Costanza B, Rademaker G, Durieux F, Agirman F, Maloujahmoum N, Cusumano PG, Lovinfosse P, Leung HY, Lambert F, Bours V, Schalkwijk CG, Hustinx R, Peulen O, Castronovo V, Bellahcène A. Bellier J, et al. Cell Rep. 2020 Feb 4;30(5):1400-1416.e6. doi: 10.1016/j.celrep.2020.01.012. Cell Rep. 2020. PMID: 32023458 Free article.
78 results