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Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.
Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A. Nokin MJ, et al. Among authors: delvenne p. Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7. Breast Cancer Res. 2019. PMID: 30674353 Free PMC article.
Myoferlin is a key regulator of EGFR activity in breast cancer.
Turtoi A, Blomme A, Bellahcène A, Gilles C, Hennequière V, Peixoto P, Bianchi E, Noel A, De Pauw E, Lifrange E, Delvenne P, Castronovo V. Turtoi A, et al. Among authors: delvenne p. Cancer Res. 2013 Sep 1;73(17):5438-48. doi: 10.1158/0008-5472.CAN-13-1142. Epub 2013 Jul 17. Cancer Res. 2013. PMID: 23864327 Free article.
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A. Nokin MJ, et al. Among authors: delvenne p. Elife. 2016 Oct 19;5:e19375. doi: 10.7554/eLife.19375. Elife. 2016. PMID: 27759563 Free PMC article.
Transforming growth factor beta-induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration.
Costanza B, Rademaker G, Tiamiou A, De Tullio P, Leenders J, Blomme A, Bellier J, Bianchi E, Turtoi A, Delvenne P, Bellahcène A, Peulen O, Castronovo V. Costanza B, et al. Among authors: delvenne p. Int J Cancer. 2019 Sep 15;145(6):1570-1584. doi: 10.1002/ijc.32247. Epub 2019 Mar 28. Int J Cancer. 2019. PMID: 30834519 Free article.
Differential proteomic analysis of a human breast tumor and its matched bone metastasis identifies cell membrane and extracellular proteins associated with bone metastasis.
Dumont B, Castronovo V, Peulen O, Blétard N, Clézardin P, Delvenne P, De Pauw EA, Turtoi A, Bellahcène A. Dumont B, et al. Among authors: delvenne p. J Proteome Res. 2012 Apr 6;11(4):2247-60. doi: 10.1021/pr201022n. Epub 2012 Mar 9. J Proteome Res. 2012. PMID: 22356681 Free article.
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.
Chiavarina B, Nokin MJ, Bellier J, Durieux F, Bletard N, Sherer F, Lovinfosse P, Peulen O, Verset L, Dehon R, Demetter P, Turtoi A, Uchida K, Goldman S, Hustinx R, Delvenne P, Castronovo V, Bellahcène A. Chiavarina B, et al. Among authors: delvenne p. Int J Mol Sci. 2017 Jan 21;18(1):213. doi: 10.3390/ijms18010213. Int J Mol Sci. 2017. PMID: 28117708 Free PMC article.
345 results