Bery N - Search Results

1

Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH. Cruz-Migoni A, et al. Among authors: bery n. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2545-2550. doi: 10.1073/pnas.1811360116. Epub 2019 Jan 25. Proc Natl Acad Sci U S A. 2019. PMID: 30683716 Free PMC article.

2

BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.

Bery N, Cruz-Migoni A, Bataille CJ, Quevedo CE, Tulmin H, Miller A, Russell A, Phillips SE, Carr SB, Rabbitts TH. Bery N, et al. Elife. 2018 Jul 10;7:e37122. doi: 10.7554/eLife.37122. Elife. 2018. PMID: 29989546 Free PMC article.

3

Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.

Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, Rabbitts TH. Quevedo CE, et al. Among authors: bery n. Nat Commun. 2018 Aug 9;9(1):3169. doi: 10.1038/s41467-018-05707-2. Nat Commun. 2018. PMID: 30093669 Free PMC article.

4

Bioluminescence Resonance Energy Transfer 2 (BRET2)-Based RAS Biosensors to Characterize RAS Inhibitors.

Bery N, Rabbitts TH. Bery N, et al. Curr Protoc Cell Biol. 2019 Jun;83(1):e83. doi: 10.1002/cpcb.83. Epub 2019 Feb 15. Curr Protoc Cell Biol. 2019. PMID: 30768855

5

A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2.

Bery N, Bataille CJR, Russell A, Hayes A, Raynaud F, Milhas S, Anand S, Tulmin H, Miller A, Rabbitts TH. Bery N, et al. Sci Adv. 2021 Apr 9;7(15):eabg1950. doi: 10.1126/sciadv.abg1950. Print 2021 Apr. Sci Adv. 2021. PMID: 33837087 Free PMC article.

6

KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.

Bery N, Legg S, Debreczeni J, Breed J, Embrey K, Stubbs C, Kolasinska-Zwierz P, Barrett N, Marwood R, Watson J, Tart J, Overman R, Miller A, Phillips C, Minter R, Rabbitts TH. Bery N, et al. Nat Commun. 2019 Jun 13;10(1):2607. doi: 10.1038/s41467-019-10419-2. Nat Commun. 2019. PMID: 31197133 Free PMC article.

7

Competitive SPR using an intracellular anti-LMO2 antibody identifies novel LMO2-interacting compounds.

Canning P, Bataille C, Bery N, Milhas S, Hayes A, Raynaud F, Miller A, Rabbitts T. Canning P, et al. Among authors: bery n. J Immunol Methods. 2021 Jul;494:113051. doi: 10.1016/j.jim.2021.113051. Epub 2021 Mar 29. J Immunol Methods. 2021. PMID: 33794223 Free PMC article.

8

A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS.

Bery N, Miller A, Rabbitts T. Bery N, et al. Nat Commun. 2020 Jun 26;11(1):3233. doi: 10.1038/s41467-020-17022-w. Nat Commun. 2020. PMID: 32591521 Free PMC article.

9

Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange.

Guillard S, Kolasinska-Zwierz P, Debreczeni J, Breed J, Zhang J, Bery N, Marwood R, Tart J, Overman R, Stocki P, Mistry B, Phillips C, Rabbitts T, Jackson R, Minter R. Guillard S, et al. Among authors: bery n. Nat Commun. 2017 Jul 14;8:16111. doi: 10.1038/ncomms16111. Nat Commun. 2017. PMID: 28706291 Free PMC article.

10

Selection and Characterization of a Nanobody Biosensor of GTP-Bound RHO Activities.

Keller L, Bery N, Tardy C, Ligat L, Favre G, Rabbitts TH, Olichon A. Keller L, et al. Among authors: bery n. Antibodies (Basel). 2019 Jan 9;8(1):8. doi: 10.3390/antib8010008. Antibodies (Basel). 2019. PMID: 31544814 Free PMC article.

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