Le Roch KG - Search Results

1

Comparative 3D genome organization in apicomplexan parasites.

Bunnik EM, Venkat A, Shao J, McGovern KE, Batugedara G, Worth D, Prudhomme J, Lapp SA, Andolina C, Ross LS, Lawres L, Brady D, Sinnis P, Nosten F, Fidock DA, Wilson EH, Tewari R, Galinski MR, Ben Mamoun C, Ay F, Le Roch KG. Bunnik EM, et al. Among authors: le roch kg. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3183-3192. doi: 10.1073/pnas.1810815116. Epub 2019 Feb 5. Proc Natl Acad Sci U S A. 2019. PMID: 30723152 Free PMC article.

2

Marine actinomycetes: a new source of compounds against the human malaria parasite.

Prudhomme J, McDaniel E, Ponts N, Bertani S, Fenical W, Jensen P, Le Roch K. Prudhomme J, et al. PLoS One. 2008 Jun 4;3(6):e2335. doi: 10.1371/journal.pone.0002335. PLoS One. 2008. PMID: 18523554 Free PMC article.

3

Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence.

Ponts N, Yang J, Chung DW, Prudhomme J, Girke T, Horrocks P, Le Roch KG. Ponts N, et al. Among authors: le roch kg. PLoS One. 2008 Jun 11;3(6):e2386. doi: 10.1371/journal.pone.0002386. PLoS One. 2008. PMID: 18545708 Free PMC article.

4

A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum.

Le Roch KG, Johnson JR, Ahiboh H, Chung DW, Prudhomme J, Plouffe D, Henson K, Zhou Y, Witola W, Yates JR, Mamoun CB, Winzeler EA, Vial H. Le Roch KG, et al. BMC Genomics. 2008 Oct 30;9:513. doi: 10.1186/1471-2164-9-513. BMC Genomics. 2008. PMID: 18973684 Free PMC article.

5

Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus.

Lane AL, Stout EP, Lin AS, Prudhomme J, Le Roch K, Fairchild CR, Franzblau SG, Hay ME, Aalbersberg W, Kubanek J. Lane AL, et al. J Org Chem. 2009 Apr 3;74(7):2736-42. doi: 10.1021/jo900008w. J Org Chem. 2009. PMID: 19271727 Free PMC article.

6

High-content live cell imaging with RNA probes: advancements in high-throughput antimalarial drug discovery.

Cervantes S, Prudhomme J, Carter D, Gopi KG, Li Q, Chang YT, Le Roch KG. Cervantes S, et al. Among authors: le roch kg. BMC Cell Biol. 2009 Jun 10;10:45. doi: 10.1186/1471-2121-10-45. BMC Cell Biol. 2009. PMID: 19515257 Free PMC article.

7

Nucleosome landscape and control of transcription in the human malaria parasite.

Ponts N, Harris EY, Prudhomme J, Wick I, Eckhardt-Ludka C, Hicks GR, Hardiman G, Lonardi S, Le Roch KG. Ponts N, et al. Among authors: le roch kg. Genome Res. 2010 Feb;20(2):228-38. doi: 10.1101/gr.101063.109. Epub 2010 Jan 6. Genome Res. 2010. PMID: 20054063 Free PMC article.

8

Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.

Lin AS, Stout EP, Prudhomme J, Le Roch K, Fairchild CR, Franzblau SG, Aalbersberg W, Hay ME, Kubanek J. Lin AS, et al. J Nat Prod. 2010 Feb 26;73(2):275-8. doi: 10.1021/np900686w. J Nat Prod. 2010. PMID: 20141173 Free PMC article.

9

Nucleosome occupancy at transcription start sites in the human malaria parasite: a hard-wired evolution of virulence?

Ponts N, Harris EY, Lonardi S, Le Roch KG. Ponts N, et al. Among authors: le roch kg. Infect Genet Evol. 2011 Jun;11(4):716-24. doi: 10.1016/j.meegid.2010.08.002. Epub 2010 Aug 11. Infect Genet Evol. 2011. PMID: 20708104 Free PMC article.

10

Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum.

Stout EP, Cervantes S, Prudhomme J, France S, La Clair JJ, Le Roch K, Kubanek J. Stout EP, et al. ChemMedChem. 2011 Sep 5;6(9):1572-7. doi: 10.1002/cmdc.201100252. Epub 2011 Jul 5. ChemMedChem. 2011. PMID: 21732541 Free PMC article. No abstract available.

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