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Metopimazine is primarily metabolized by a liver amidase in humans.
Busby RW, Cai X, Yang S, Ramos L, Venkatarangan L, Shen H, Wax S, Sadeque AJM, De Colle C. Busby RW, et al. Among authors: shen h. Pharmacol Res Perspect. 2022 Feb;10(1):e00903. doi: 10.1002/prp2.903. Pharmacol Res Perspect. 2022. PMID: 34918875 Free PMC article. Clinical Trial.
Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.
Ma J, Zhang X, Soloveva V, Warren T, Guo F, Wu S, Lu H, Guo J, Su Q, Shen H, Solon E, Comunale MA, Mehta A, Guo JT, Bavari S, Du Y, Block TM, Chang J. Ma J, et al. Among authors: shen h. Antiviral Res. 2018 Feb;150:112-122. doi: 10.1016/j.antiviral.2017.12.008. Epub 2017 Dec 15. Antiviral Res. 2018. PMID: 29253498 Free PMC article.
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