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Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition.
Gräb J, Suárez I, van Gumpel E, Winter S, Schreiber F, Esser A, Hölscher C, Fritsch M, Herb M, Schramm M, Wachsmuth L, Pallasch C, Pasparakis M, Kashkar H, Rybniker J. Gräb J, et al. Among authors: pasparakis m. Nat Commun. 2019 Feb 8;10(1):688. doi: 10.1038/s41467-019-08405-9. Nat Commun. 2019. PMID: 30737374 Free PMC article.
Epithelial NEMO links innate immunity to chronic intestinal inflammation.
Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M. Nenci A, et al. Among authors: pasparakis m. Nature. 2007 Mar 29;446(7135):557-61. doi: 10.1038/nature05698. Epub 2007 Mar 14. Nature. 2007. PMID: 17361131 Free article.
TNF-induced target cell killing by CTL activated through cross-presentation.
Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Nieswandt B, van Rooijen N, Limmer A, Cederbrant K, Heikenwalder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA. Wohlleber D, et al. Among authors: pasparakis m. Cell Rep. 2012 Sep 27;2(3):478-87. doi: 10.1016/j.celrep.2012.08.001. Epub 2012 Aug 30. Cell Rep. 2012. PMID: 22939982 Free article.
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, Eftychi C, Lin J, Corona T, Hermance N, Zelic M, Kirsch P, Basic M, Bleich A, Kelliher M, Pasparakis M. Dannappel M, et al. Among authors: pasparakis m. Nature. 2014 Sep 4;513(7516):90-4. doi: 10.1038/nature13608. Epub 2014 Aug 17. Nature. 2014. PMID: 25132550 Free PMC article.
Necroptosis and its role in inflammation.
Pasparakis M, Vandenabeele P. Pasparakis M, et al. Nature. 2015 Jan 15;517(7534):311-20. doi: 10.1038/nature14191. Nature. 2015. PMID: 25592536 Review.
The tumour suppressor CYLD regulates the p53 DNA damage response.
Fernández-Majada V, Welz PS, Ermolaeva MA, Schell M, Adam A, Dietlein F, Komander D, Büttner R, Thomas RK, Schumacher B, Pasparakis M. Fernández-Majada V, et al. Among authors: pasparakis m. Nat Commun. 2016 Aug 26;7:12508. doi: 10.1038/ncomms12508. Nat Commun. 2016. PMID: 27561390 Free PMC article.
201 results