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Functional interactions between scaffold proteins, noncoding RNAs, and genome loci induce liquid-liquid phase separation as organizing principle for 3-dimensional nuclear architecture: implications in cancer.
Rubio K, Dobersch S, Barreto G. Rubio K, et al. Among authors: barreto g. FASEB J. 2019 May;33(5):5814-5822. doi: 10.1096/fj.201802715R. Epub 2019 Feb 11. FASEB J. 2019. PMID: 30742773 Review.
We also discuss the implications in different cancer types as well as the potential use of this knowledge to develop novel therapeutic strategies against cancer.-Rubio, K., Dobersch, S., Barreto, G. Functional interactions between scaffold proteins, noncoding RNAs, …
We also discuss the implications in different cancer types as well as the potential use of this knowledge to develop novel therapeutic strat …
Epigenetics in lung cancer diagnosis and therapy.
Mehta A, Dobersch S, Romero-Olmedo AJ, Barreto G. Mehta A, et al. Among authors: barreto g. Cancer Metastasis Rev. 2015 Jun;34(2):229-41. doi: 10.1007/s10555-015-9563-3. Cancer Metastasis Rev. 2015. PMID: 25939322 Review.
Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate.
Mehta A, Cordero J, Dobersch S, Romero-Olmedo AJ, Savai R, Bodner J, Chao CM, Fink L, Guzmán-Díaz E, Singh I, Dobreva G, Rapp UR, Günther S, Ilinskaya ON, Bellusci S, Dammann RH, Braun T, Seeger W, Gattenlöhner S, Tresch A, Günther A, Barreto G. Mehta A, et al. Among authors: barreto g. EMBO Mol Med. 2016 Dec 1;8(12):1380-1389. doi: 10.15252/emmm.201606382. Print 2016 Dec. EMBO Mol Med. 2016. PMID: 27821429 Free PMC article.
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.
Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, Mehta A, Wujak L, Cabrera-Fuentes H, Chao CM, Braubach P, Bellusci S, Seeger W, Günther A, Preissner KT, Wygrecka M, Savai R, Papy-Garcia D, Dobreva G, Heikenwalder M, Savai-Pullamsetti S, Braun T, Barreto G. Rubio K, et al. Among authors: barreto g. Nat Commun. 2019 May 20;10(1):2229. doi: 10.1038/s41467-019-10066-7. Nat Commun. 2019. PMID: 31110176 Free PMC article.
Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation.
Dobersch S, Rubio K, Singh I, Günther S, Graumann J, Cordero J, Castillo-Negrete R, Huynh MB, Mehta A, Braubach P, Cabrera-Fuentes H, Bernhagen J, Chao CM, Bellusci S, Günther A, Preissner KT, Kugel S, Dobreva G, Wygrecka M, Braun T, Papy-Garcia D, Barreto G. Dobersch S, et al. Among authors: barreto g. Nat Commun. 2021 Feb 16;12(1):1072. doi: 10.1038/s41467-021-21227-y. Nat Commun. 2021. PMID: 33594057 Free PMC article.
561 results