Clark SJ - Search Results

1

Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity.

Linker SM, Urban L, Clark SJ, Chhatriwala M, Amatya S, McCarthy DJ, Ebersberger I, Vallier L, Reik W, Stegle O, Bonder MJ. Linker SM, et al. Among authors: clark sj. Genome Biol. 2019 Feb 11;20(1):30. doi: 10.1186/s13059-019-1644-0. Genome Biol. 2019. PMID: 30744673 Free PMC article.

2

Genome-wide bisulfite sequencing in zygotes identifies demethylation targets and maps the contribution of TET3 oxidation.

Peat JR, Dean W, Clark SJ, Krueger F, Smallwood SA, Ficz G, Kim JK, Marioni JC, Hore TA, Reik W. Peat JR, et al. Among authors: clark sj. Cell Rep. 2014 Dec 24;9(6):1990-2000. doi: 10.1016/j.celrep.2014.11.034. Epub 2014 Dec 12. Cell Rep. 2014. PMID: 25497087 Free PMC article.

3

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.

Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood S, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W. Angermueller C, et al. Among authors: clark sj. Nat Methods. 2016 Mar;13(3):229-232. doi: 10.1038/nmeth.3728. Epub 2016 Jan 11. Nat Methods. 2016. PMID: 26752769 Free PMC article.

4

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity.

Clark SJ, Lee HJ, Smallwood SA, Kelsey G, Reik W. Clark SJ, et al. Genome Biol. 2016 Apr 18;17:72. doi: 10.1186/s13059-016-0944-x. Genome Biol. 2016. PMID: 27091476 Free PMC article. Review.

5

Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).

Clark SJ, Smallwood SA, Lee HJ, Krueger F, Reik W, Kelsey G. Clark SJ, et al. Nat Protoc. 2017 Mar;12(3):534-547. doi: 10.1038/nprot.2016.187. Epub 2017 Feb 9. Nat Protoc. 2017. PMID: 28182018

6

Multi-tissue DNA methylation age predictor in mouse.

Stubbs TM, Bonder MJ, Stark AK, Krueger F; BI Ageing Clock Team; von Meyenn F, Stegle O, Reik W. Stubbs TM, et al. Genome Biol. 2017 Apr 11;18(1):68. doi: 10.1186/s13059-017-1203-5. Genome Biol. 2017. PMID: 28399939 Free PMC article.

7

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells.

Clark SJ, Argelaguet R, Kapourani CA, Stubbs TM, Lee HJ, Alda-Catalinas C, Krueger F, Sanguinetti G, Kelsey G, Marioni JC, Stegle O, Reik W. Clark SJ, et al. Nat Commun. 2018 Feb 22;9(1):781. doi: 10.1038/s41467-018-03149-4. Nat Commun. 2018. PMID: 29472610 Free PMC article.

8

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.

Rulands S, Lee HJ, Clark SJ, Angermueller C, Smallwood SA, Krueger F, Mohammed H, Dean W, Nichols J, Rugg-Gunn P, Kelsey G, Stegle O, Simons BD, Reik W. Rulands S, et al. Among authors: clark sj. Cell Syst. 2018 Jul 25;7(1):63-76.e12. doi: 10.1016/j.cels.2018.06.012. Cell Syst. 2018. PMID: 30031774 Free PMC article.

9

Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells.

Hernando-Herraez I, Evano B, Stubbs T, Commere PH, Jan Bonder M, Clark S, Andrews S, Tajbakhsh S, Reik W. Hernando-Herraez I, et al. Nat Commun. 2019 Sep 25;10(1):4361. doi: 10.1038/s41467-019-12293-4. Nat Commun. 2019. PMID: 31554804 Free PMC article.

10

Multi-omics profiling of mouse gastrulation at single-cell resolution.

Argelaguet R, Clark SJ, Mohammed H, Stapel LC, Krueger C, Kapourani CA, Imaz-Rosshandler I, Lohoff T, Xiang Y, Hanna CW, Smallwood S, Ibarra-Soria X, Buettner F, Sanguinetti G, Xie W, Krueger F, Göttgens B, Rugg-Gunn PJ, Kelsey G, Dean W, Nichols J, Stegle O, Marioni JC, Reik W. Argelaguet R, et al. Among authors: clark sj. Nature. 2019 Dec;576(7787):487-491. doi: 10.1038/s41586-019-1825-8. Epub 2019 Dec 11. Nature. 2019. PMID: 31827285 Free PMC article.

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