Stegle O - Search Results

1

Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity.

Linker SM, Urban L, Clark SJ, Chhatriwala M, Amatya S, McCarthy DJ, Ebersberger I, Vallier L, Reik W, Stegle O, Bonder MJ. Linker SM, et al. Among authors: stegle o. Genome Biol. 2019 Feb 11;20(1):30. doi: 10.1186/s13059-019-1644-0. Genome Biol. 2019. PMID: 30744673 Free PMC article.

2

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity.

Smallwood SA, Lee HJ, Angermueller C, Krueger F, Saadeh H, Peat J, Andrews SR, Stegle O, Reik W, Kelsey G. Smallwood SA, et al. Among authors: stegle o. Nat Methods. 2014 Aug;11(8):817-820. doi: 10.1038/nmeth.3035. Epub 2014 Jul 20. Nat Methods. 2014. PMID: 25042786 Free PMC article.

3

Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells.

Buettner F, Natarajan KN, Casale FP, Proserpio V, Scialdone A, Theis FJ, Teichmann SA, Marioni JC, Stegle O. Buettner F, et al. Among authors: stegle o. Nat Biotechnol. 2015 Feb;33(2):155-60. doi: 10.1038/nbt.3102. Epub 2015 Jan 19. Nat Biotechnol. 2015. PMID: 25599176

4

Computational and analytical challenges in single-cell transcriptomics.

Stegle O, Teichmann SA, Marioni JC. Stegle O, et al. Nat Rev Genet. 2015 Mar;16(3):133-45. doi: 10.1038/nrg3833. Epub 2015 Jan 28. Nat Rev Genet. 2015. PMID: 25628217 Review.

5

Computational assignment of cell-cycle stage from single-cell transcriptome data.

Scialdone A, Natarajan KN, Saraiva LR, Proserpio V, Teichmann SA, Stegle O, Marioni JC, Buettner F. Scialdone A, et al. Among authors: stegle o. Methods. 2015 Sep 1;85:54-61. doi: 10.1016/j.ymeth.2015.06.021. Epub 2015 Jul 2. Methods. 2015. PMID: 26142758 Free article.

6

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.

Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood S, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W. Angermueller C, et al. Among authors: stegle o. Nat Methods. 2016 Mar;13(3):229-232. doi: 10.1038/nmeth.3728. Epub 2016 Jan 11. Nat Methods. 2016. PMID: 26752769 Free PMC article.

7

Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression.

Rakitsch B, Stegle O. Rakitsch B, et al. Among authors: stegle o. Genome Biol. 2016 Feb 24;17:33. doi: 10.1186/s13059-016-0895-2. Genome Biol. 2016. PMID: 26911988 Free PMC article.

8

Limited Contribution of DNA Methylation Variation to Expression Regulation in Arabidopsis thaliana.

Meng D, Dubin M, Zhang P, Osborne EJ, Stegle O, Clark RM, Nordborg M. Meng D, et al. Among authors: stegle o. PLoS Genet. 2016 Jul 11;12(7):e1006141. doi: 10.1371/journal.pgen.1006141. eCollection 2016 Jul. PLoS Genet. 2016. PMID: 27398721 Free PMC article.

9

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.

Ecker S, Chen L, Pancaldi V, Bagger FO, Fernández JM, Carrillo de Santa Pau E, Juan D, Mann AL, Watt S, Casale FP, Sidiropoulos N, Rapin N, Merkel A; BLUEPRINT Consortium; Stunnenberg HG, Stegle O, Frontini M, Downes K, Pastinen T, Kuijpers TW, Rico D, Valencia A, Beck S, Soranzo N, Paul DS. Ecker S, et al. Among authors: stegle o. Genome Biol. 2017 Jan 26;18(1):18. doi: 10.1186/s13059-017-1156-8. Genome Biol. 2017. PMID: 28126036 Free PMC article.

10

DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning.

Angermueller C, Lee HJ, Reik W, Stegle O. Angermueller C, et al. Among authors: stegle o. Genome Biol. 2017 Apr 11;18(1):67. doi: 10.1186/s13059-017-1189-z. Genome Biol. 2017. PMID: 28395661 Free PMC article.

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