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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Hinohara K, Wu HJ, Sébastien Vigneau, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K. Hinohara K, et al. Among authors: jeselsohn r. Cancer Cell. 2019 Feb 11;35(2):330-332. doi: 10.1016/j.ccell.2019.01.012. Cancer Cell. 2019. PMID: 30753830 Free PMC article. No abstract available.
ESR1 activating mutations: From structure to clinical application.
Grinshpun A, Chen V, Sandusky ZM, Fanning SW, Jeselsohn R. Grinshpun A, et al. Among authors: jeselsohn r. Biochim Biophys Acta Rev Cancer. 2023 Jan;1878(1):188830. doi: 10.1016/j.bbcan.2022.188830. Epub 2022 Nov 4. Biochim Biophys Acta Rev Cancer. 2023. PMID: 36336145 Free article. Review.
How drug resistance takes shape.
Jeselsohn R, Brown M. Jeselsohn R, et al. Elife. 2016 Mar 24;5:e14973. doi: 10.7554/eLife.14973. Elife. 2016. PMID: 27010172 Free PMC article.
Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations.
Jeselsohn R, Bergholz JS, Pun M, Cornwell M, Liu W, Nardone A, Xiao T, Li W, Qiu X, Buchwalter G, Feiglin A, Abell-Hart K, Fei T, Rao P, Long H, Kwiatkowski N, Zhang T, Gray N, Melchers D, Houtman R, Liu XS, Cohen O, Wagle N, Winer EP, Zhao J, Brown M. Jeselsohn R, et al. Cancer Cell. 2018 Feb 12;33(2):173-186.e5. doi: 10.1016/j.ccell.2018.01.004. Cancer Cell. 2018. PMID: 29438694 Free PMC article.
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K. Hinohara K, et al. Among authors: jeselsohn r. Cancer Cell. 2018 Dec 10;34(6):939-953.e9. doi: 10.1016/j.ccell.2018.10.014. Epub 2018 Nov 21. Cancer Cell. 2018. PMID: 30472020 Free PMC article.
Mathematical Modeling Identifies Optimum Palbociclib-fulvestrant Dose Administration Schedules for the Treatment of Patients with Estrogen Receptor-positive Breast Cancer.
Cheng YC, Stein S, Nardone A, Liu W, Ma W, Cohen G, Guarducci C, McDonald TO, Jeselsohn R, Michor F. Cheng YC, et al. Among authors: jeselsohn r. Cancer Res Commun. 2023 Nov 16;3(11):2331-2344. doi: 10.1158/2767-9764.CRC-23-0257. Cancer Res Commun. 2023. PMID: 37921419 Free PMC article.
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