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Page 1
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ. Whiteley AT, et al. Among authors: de oliveira mann cc. Nature. 2019 Mar;567(7747):194-199. doi: 10.1038/s41586-019-0953-5. Epub 2019 Feb 20. Nature. 2019. PMID: 30787435 Free PMC article.
Correction: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.
Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. Kessler N, et al. Among authors: de oliveira mann cc. J Exp Med. 2022 Dec 5;219(12):e2022075911022022c. doi: 10.1084/jem.2022075911022022c. Epub 2022 Nov 11. J Exp Med. 2022. PMID: 36367753 Free PMC article. No abstract available.
Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Civril F, et al. Among authors: de oliveira mann cc. Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30. Nature. 2013. PMID: 23722159 Free PMC article.
cGAS Conducts Micronuclei DNA Surveillance.
de Oliveira Mann CC, Kranzusch PJ. de Oliveira Mann CC, et al. Trends Cell Biol. 2017 Oct;27(10):697-698. doi: 10.1016/j.tcb.2017.08.007. Epub 2017 Sep 4. Trends Cell Biol. 2017. PMID: 28882413
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Andreeva L, et al. Among authors: de oliveira mann cc. Nature. 2017 Sep 21;549(7672):394-398. doi: 10.1038/nature23890. Epub 2017 Sep 13. Nature. 2017. PMID: 28902841
cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Li Y, Slavik KM, Toyoda HC, Morehouse BR, de Oliveira Mann CC, Elek A, Levy S, Wang Z, Mears KS, Liu J, Kashin D, Guo X, Mass T, Sebé-Pedrós A, Schwede F, Kranzusch PJ. Li Y, et al. Among authors: de oliveira mann cc. Cell. 2023 Jul 20;186(15):3261-3276.e20. doi: 10.1016/j.cell.2023.05.038. Epub 2023 Jun 27. Cell. 2023. PMID: 37379839 Free PMC article.
Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Michalski S, de Oliveira Mann CC, Stafford CA, Witte G, Bartho J, Lammens K, Hornung V, Hopfner KP. Michalski S, et al. Among authors: de oliveira mann cc. Nature. 2020 Nov;587(7835):678-682. doi: 10.1038/s41586-020-2748-0. Epub 2020 Sep 10. Nature. 2020. PMID: 32911480
ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling.
Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Moreau T, Rodero MP, Rösler R, Wiese S, Volpi S, Gattorno M, Papa R, Lynch SA, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, de Oliveira Mann CC, Crow YJ, Sparrer KMJ. Hirschenberger M, et al. Among authors: de oliveira mann cc. Nat Commun. 2023 Nov 1;14(1):6770. doi: 10.1038/s41467-023-42150-4. Nat Commun. 2023. PMID: 37914730 Free PMC article.
24 results