Botella L - Search Results

1

An NAD⁺ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.

Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schnappinger D, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O. Freire DM, et al. Among authors: botella l. Mol Cell. 2019 Mar 21;73(6):1282-1291.e8. doi: 10.1016/j.molcel.2019.01.028. Epub 2019 Feb 18. Mol Cell. 2019. PMID: 30792174 Free PMC article.

2

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.

Botella L, Vaubourgeix J, Livny J, Schnappinger D. Botella L, et al. Nat Commun. 2017 Mar 28;8:14731. doi: 10.1038/ncomms14731. Nat Commun. 2017. PMID: 28348398 Free PMC article.

3

Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death.

Zaveri A, Wang R, Botella L, Sharma R, Zhu L, Wallach JB, Song N, Jansen RS, Rhee KY, Ehrt S, Schnappinger D. Zaveri A, et al. Among authors: botella l. Mol Microbiol. 2020 Oct;114(4):641-652. doi: 10.1111/mmi.14571. Epub 2020 Jul 28. Mol Microbiol. 2020. PMID: 32634279 Free PMC article.

4

Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages.

Pellegrino E, Aylan B, Bussi C, Fearns A, Bernard EM, Athanasiadi N, Santucci P, Botella L, Gutierrez MG. Pellegrino E, et al. Among authors: botella l. J Cell Biol. 2023 Dec 4;222(12):e202303066. doi: 10.1083/jcb.202303066. Epub 2023 Sep 22. J Cell Biol. 2023. PMID: 37737955 Free PMC article.

5

Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin.

Qu D, Ge P, Botella L, Park SW, Lee HN, Thornton N, Bean JM, Krieger IV, Sacchettini JC, Ehrt S, Aldrich CC, Schnappinger D. Qu D, et al. Among authors: botella l. Nat Commun. 2024 May 16;15(1):4161. doi: 10.1038/s41467-024-48448-1. Nat Commun. 2024. PMID: 38755122 Free PMC article.

6

The nonredundant roles of two 4'-phosphopantetheinyl transferases in vital processes of Mycobacteria.

Chalut C, Botella L, de Sousa-D'Auria C, Houssin C, Guilhot C. Chalut C, et al. Among authors: botella l. Proc Natl Acad Sci U S A. 2006 May 30;103(22):8511-6. doi: 10.1073/pnas.0511129103. Epub 2006 May 18. Proc Natl Acad Sci U S A. 2006. PMID: 16709676 Free PMC article.

7

Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis.

Santucci P, Aylan B, Botella L, Bernard EM, Bussi C, Pellegrino E, Athanasiadi N, Gutierrez MG. Santucci P, et al. Among authors: botella l. mBio. 2022 Apr 26;13(2):e0011722. doi: 10.1128/mbio.00117-22. Epub 2022 Mar 24. mBio. 2022. PMID: 35323041 Free PMC article.

8

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway.

Puissegur MP, Lay G, Gilleron M, Botella L, Nigou J, Marrakchi H, Mari B, Duteyrat JL, Guerardel Y, Kremer L, Barbry P, Puzo G, Altare F. Puissegur MP, et al. Among authors: botella l. J Immunol. 2007 Mar 1;178(5):3161-9. doi: 10.4049/jimmunol.178.5.3161. J Immunol. 2007. PMID: 17312164

9

Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.

Queval CJ, Fearns A, Botella L, Smyth A, Schnettger L, Mitermite M, Wooff E, Villarreal-Ramos B, Garcia-Jimenez W, Heunis T, Trost M, Werling D, Salguero FJ, Gordon SV, Gutierrez MG. Queval CJ, et al. Among authors: botella l. PLoS Pathog. 2021 Mar 15;17(3):e1009410. doi: 10.1371/journal.ppat.1009410. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33720986 Free PMC article.

10

MptpB Inhibitor Improves the Action of Antibiotics against Mycobacterium tuberculosis and Nontuberculous Mycobacterium avium Infections.

Rodríguez-Fernández P, Botella L, Cavet JS, Domínguez J, Gutierrez MG, Suckling CJ, Scott FJ, Tabernero L. Rodríguez-Fernández P, et al. Among authors: botella l. ACS Infect Dis. 2024 Jan 12;10(1):170-183. doi: 10.1021/acsinfecdis.3c00446. Epub 2023 Dec 12. ACS Infect Dis. 2024. PMID: 38085851 Free PMC article.

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