Jonsson MK - Search Results

1

The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs.

Goversen B, Jonsson MK, van den Heuvel NH, Rijken R, Vos MA, van Veen TA, de Boer TP. Goversen B, et al. Among authors: jonsson mk. Prog Biophys Mol Biol. 2019 Dec;149:86-98. doi: 10.1016/j.pbiomolbio.2019.02.003. Epub 2019 Feb 27. Prog Biophys Mol Biol. 2019. PMID: 30826123

2

Rewiring the heart: stem cell therapy to restore normal cardiac excitability and conduction.

Blank AC, van Veen TA, Jonsson MK, Zelen JS, Strengers JL, de Boer TP, van der Heyden MA. Blank AC, et al. Among authors: jonsson mk. Curr Stem Cell Res Ther. 2009 Jan;4(1):23-33. doi: 10.2174/157488809787169066. Curr Stem Cell Res Ther. 2009. PMID: 19149627 Review.

3

Human cardiomyocyte progenitor cell-derived cardiomyocytes display a maturated electrical phenotype.

de Boer TP, van Veen TA, Jonsson MK, Kok BG, Metz CH, Sluijter JP, Doevendans PA, de Bakker JM, Goumans MJ, van der Heyden MA. de Boer TP, et al. Among authors: jonsson mk. J Mol Cell Cardiol. 2010 Jan;48(1):254-60. doi: 10.1016/j.yjmcc.2009.05.004. Epub 2009 May 19. J Mol Cell Cardiol. 2010. PMID: 19460390

4

Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes.

Jonsson MK, Duker G, Tropp C, Andersson B, Sartipy P, Vos MA, van Veen TA. Jonsson MK, et al. Stem Cell Res. 2010 May;4(3):189-200. doi: 10.1016/j.scr.2010.02.001. Epub 2010 Feb 17. Stem Cell Res. 2010. PMID: 20303332 Free article.

5

Gender disparity in cardiac electrophysiology: implications for cardiac safety pharmacology.

Jonsson MK, Vos MA, Duker G, Demolombe S, van Veen TA. Jonsson MK, et al. Pharmacol Ther. 2010 Jul;127(1):9-18. doi: 10.1016/j.pharmthera.2010.04.002. Epub 2010 May 10. Pharmacol Ther. 2010. PMID: 20462510 Review.

6

Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes.

Nalos L, Varkevisser R, Jonsson MK, Houtman MJ, Beekman JD, van der Nagel R, Thomsen MB, Duker G, Sartipy P, de Boer TP, Peschar M, Rook MB, van Veen TA, van der Heyden MA, Vos MA. Nalos L, et al. Among authors: jonsson mk. Br J Pharmacol. 2012 Jan;165(2):467-78. doi: 10.1111/j.1476-5381.2011.01558.x. Br J Pharmacol. 2012. PMID: 21718297 Free PMC article.

7

Epigenetics: DNA demethylation promotes skeletal myotube maturation.

Hupkes M, Jonsson MK, Scheenen WJ, van Rotterdam W, Sotoca AM, van Someren EP, van der Heyden MA, van Veen TA, van Ravestein-van Os RI, Bauerschmidt S, Piek E, Ypey DL, van Zoelen EJ, Dechering KJ. Hupkes M, et al. Among authors: jonsson mk. FASEB J. 2011 Nov;25(11):3861-72. doi: 10.1096/fj.11-186122. Epub 2011 Jul 27. FASEB J. 2011. PMID: 21795504

8

Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG.

Jonsson MK, Vos MA, Mirams GR, Duker G, Sartipy P, de Boer TP, van Veen TA. Jonsson MK, et al. J Mol Cell Cardiol. 2012 May;52(5):998-1008. doi: 10.1016/j.yjmcc.2012.02.002. Epub 2012 Feb 14. J Mol Cell Cardiol. 2012. PMID: 22353256

9

Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current.

Jonsson MK, van der Heyden MA, van Veen TA. Jonsson MK, et al. J Mol Cell Cardiol. 2012 Sep;53(3):369-74. doi: 10.1016/j.yjmcc.2012.06.011. Epub 2012 Jun 26. J Mol Cell Cardiol. 2012. PMID: 22742967 Review.

10

Improvement of cardiac efficacy and safety models in drug discovery by the use of stem cell-derived cardiomyocytes.

Jonsson MK, van Veen TA, Goumans MJ, Vos MA, Duker G, Sartipy P. Jonsson MK, et al. Expert Opin Drug Discov. 2009 Apr;4(4):357-72. doi: 10.1517/17460440902794912. Expert Opin Drug Discov. 2009. PMID: 23485039

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