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Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors.
Rapisuwon S, Izar B, Batenchuk C, Avila A, Mei S, Sorger P, Parks JM, Cooper SJ, Wagner D, Zeck JC, Charabaty AJ, Atkins MB. Rapisuwon S, et al. Among authors: sorger p. J Immunother Cancer. 2019 Mar 4;7(1):61. doi: 10.1186/s40425-019-0533-0. J Immunother Cancer. 2019. PMID: 30832716 Free PMC article.
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, Gray JW, Guinney J, Hanlon SE, Hughes SK, Hwang ES, Iacobuzio-Donahue CA, Jané-Valbuena J, Johnson BE, Lau KS, Lively T, Mazzilli SA, Pe'er D, Santagata S, Shalek AK, Schapiro D, Snyder MP, Sorger PK, Spira AE, Srivastava S, Tan K, West RB, Williams EH; Human Tumor Atlas Network. Rozenblatt-Rosen O, et al. Among authors: sorger pk. Cell. 2020 Apr 16;181(2):236-249. doi: 10.1016/j.cell.2020.03.053. Cell. 2020. PMID: 32302568 Free PMC article. Review.
Spatial transcriptomics.
Anderson AC, Yanai I, Yates LR, Wang L, Swarbrick A, Sorger P, Santagata S, Fridman WH, Gao Q, Jerby L, Izar B, Shang L, Zhou X. Anderson AC, et al. Among authors: sorger p. Cancer Cell. 2022 Sep 12;40(9):895-900. doi: 10.1016/j.ccell.2022.08.021. Cancer Cell. 2022. PMID: 36099884 Free article.
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma.
Gaglia G, Burger ML, Ritch CC, Rammos D, Dai Y, Crossland GE, Tavana SZ, Warchol S, Jaeger AM, Naranjo S, Coy S, Nirmal AJ, Krueger R, Lin JR, Pfister H, Sorger PK, Jacks T, Santagata S. Gaglia G, et al. Cancer Cell. 2023 May 8;41(5):871-886.e10. doi: 10.1016/j.ccell.2023.03.015. Epub 2023 Apr 13. Cancer Cell. 2023. PMID: 37059105 Free PMC article.
Metabolic modulation of mitochondrial mass during CD4+ T cell activation.
Kurmi K, Liang D, van de Ven R, Georgiev P, Gassaway BM, Han S, Notarangelo G, Harris IS, Yao CH, Park JS, Hu SH, Peng J, Drijvers JM, Boswell S, Sokolov A, Dougan SK, Sorger PK, Gygi SP, Sharpe AH, Haigis MC. Kurmi K, et al. Among authors: sorger pk. Cell Chem Biol. 2023 Sep 21;30(9):1064-1075.e8. doi: 10.1016/j.chembiol.2023.08.008. Cell Chem Biol. 2023. PMID: 37716347 Free PMC article.
Ovarian cancer-derived IL-4 promotes immunotherapy resistance.
Mollaoglu G, Tepper A, Falcomatà C, Potak HT, Pia L, Amabile A, Mateus-Tique J, Rabinovich N, Park MD, LaMarche NM, Brody R, Browning L, Lin JR, Zamarin D, Sorger PK, Santagata S, Merad M, Baccarini A, Brown BD. Mollaoglu G, et al. Among authors: sorger pk. Cell. 2024 Oct 30:S0092-8674(24)01154-1. doi: 10.1016/j.cell.2024.10.006. Online ahead of print. Cell. 2024. PMID: 39481380
339 results