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PAI-1 augments mucosal damage in colitis.
Kaiko GE, Chen F, Lai CW, Chiang IL, Perrigoue J, Stojmirović A, Li K, Muegge BD, Jain U, VanDussen KL, Goggins BJ, Keely S, Weaver J, Foster PS, Lawrence DA, Liu TC, Stappenbeck TS. Kaiko GE, et al. Among authors: lawrence da. Sci Transl Med. 2019 Mar 6;11(482):eaat0852. doi: 10.1126/scitranslmed.aat0852. Sci Transl Med. 2019. PMID: 30842312 Free PMC article.
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.
Courey AJ, Horowitz JC, Kim KK, Koh TJ, Novak ML, Subbotina N, Warnock M, Xue B, Cunningham AK, Lin Y, Goldklang MP, Simon RH, Lawrence DA, Sisson TH. Courey AJ, et al. Among authors: lawrence da. Blood. 2011 Aug 25;118(8):2313-21. doi: 10.1182/blood-2010-12-324574. Epub 2011 Jul 6. Blood. 2011. PMID: 21734232 Free PMC article.
PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.
Osterholzer JJ, Christensen PJ, Lama V, Horowitz JC, Hattori N, Subbotina N, Cunningham A, Lin Y, Murdock BJ, Morey RE, Olszewski MA, Lawrence DA, Simon RH, Sisson TH. Osterholzer JJ, et al. Among authors: lawrence da. J Pathol. 2012 Oct;228(2):170-80. doi: 10.1002/path.3992. Epub 2012 Jun 6. J Pathol. 2012. PMID: 22262246 Free PMC article.
464 results