Hotta A - Search Results

1

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility.

Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, Ueda T, Gee P, Nishikawa M, Nomura M, Kitaoka F, Takahashi T, Okita K, Yoshida Y, Kaneko S, Hotta A. Xu H, et al. Among authors: hotta a. Cell Stem Cell. 2019 Apr 4;24(4):566-578.e7. doi: 10.1016/j.stem.2019.02.005. Epub 2019 Mar 7. Cell Stem Cell. 2019. PMID: 30853558 Free article.

2

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines.

Kattman SJ, Witty AD, Gagliardi M, Dubois NC, Niapour M, Hotta A, Ellis J, Keller G. Kattman SJ, et al. Among authors: hotta a. Cell Stem Cell. 2011 Feb 4;8(2):228-40. doi: 10.1016/j.stem.2010.12.008. Cell Stem Cell. 2011. PMID: 21295278 Free article.

3

Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a non-human primate.

Morizane A, Doi D, Kikuchi T, Okita K, Hotta A, Kawasaki T, Hayashi T, Onoe H, Shiina T, Yamanaka S, Takahashi J. Morizane A, et al. Among authors: hotta a. Stem Cell Reports. 2013 Sep 26;1(4):283-92. doi: 10.1016/j.stemcr.2013.08.007. eCollection 2013. Stem Cell Reports. 2013. PMID: 24319664 Free PMC article.

4

Delivery of full-length factor VIII using a piggyBac transposon vector to correct a mouse model of hemophilia A.

Matsui H, Fujimoto N, Sasakawa N, Ohinata Y, Shima M, Yamanaka S, Sugimoto M, Hotta A. Matsui H, et al. Among authors: hotta a. PLoS One. 2014 Aug 15;9(8):e104957. doi: 10.1371/journal.pone.0104957. eCollection 2014. PLoS One. 2014. PMID: 25126862 Free PMC article.

5

Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice.

Kondo T, Funayama M, Tsukita K, Hotta A, Yasuda A, Nori S, Kaneko S, Nakamura M, Takahashi R, Okano H, Yamanaka S, Inoue H. Kondo T, et al. Among authors: hotta a. Stem Cell Reports. 2014 Aug 12;3(2):242-9. doi: 10.1016/j.stemcr.2014.05.017. Epub 2014 Jun 26. Stem Cell Reports. 2014. PMID: 25254338 Free PMC article.

6

Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9.

Li HL, Fujimoto N, Sasakawa N, Shirai S, Ohkame T, Sakuma T, Tanaka M, Amano N, Watanabe A, Sakurai H, Yamamoto T, Yamanaka S, Hotta A. Li HL, et al. Among authors: hotta a. Stem Cell Reports. 2015 Jan 13;4(1):143-154. doi: 10.1016/j.stemcr.2014.10.013. Epub 2014 Nov 26. Stem Cell Reports. 2015. PMID: 25434822 Free PMC article.

7

From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing.

Hotta A, Yamanaka S. Hotta A, et al. Annu Rev Genet. 2015;49:47-70. doi: 10.1146/annurev-genet-112414-054926. Epub 2015 Sep 25. Annu Rev Genet. 2015. PMID: 26407033 Review.

8

Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases.

Ishida K, Gee P, Hotta A. Ishida K, et al. Among authors: hotta a. Int J Mol Sci. 2015 Oct 16;16(10):24751-71. doi: 10.3390/ijms161024751. Int J Mol Sci. 2015. PMID: 26501275 Free PMC article. Review.

9

Efficient genomic correction methods in human iPS cells using CRISPR-Cas9 system.

Li HL, Gee P, Ishida K, Hotta A. Li HL, et al. Among authors: hotta a. Methods. 2016 May 15;101:27-35. doi: 10.1016/j.ymeth.2015.10.015. Epub 2015 Oct 23. Methods. 2016. PMID: 26525194 Free article. Review.

10

Sall1 transiently marks undifferentiated heart precursors and regulates their fate.

Morita Y, Andersen P, Hotta A, Tsukahara Y, Sasagawa N, Hayashida N, Koga C, Nishikawa M, Saga Y, Evans SM, Koshiba-Takeuchi K, Nishinakamura R, Yoshida Y, Kwon C, Takeuchi JK. Morita Y, et al. Among authors: hotta a. J Mol Cell Cardiol. 2016 Mar;92:158-62. doi: 10.1016/j.yjmcc.2016.02.008. Epub 2016 Feb 11. J Mol Cell Cardiol. 2016. PMID: 26876450 Free PMC article.

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