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Page 1
4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides.
Meyers MJ, Liu J, Xu J, Leng F, Guan J, Liu Z, McNitt SA, Qin L, Dai L, Ma H, Adah D, Zhao S, Li X, Polino AJ, Nasamu AS, Goldberg DE, Liu X, Lu Y, Tu Z, Chen X, Tortorella MD. Meyers MJ, et al. Among authors: goldberg de. J Med Chem. 2019 Apr 11;62(7):3503-3512. doi: 10.1021/acs.jmedchem.8b01972. Epub 2019 Mar 22. J Med Chem. 2019. PMID: 30856324 Free PMC article.
Novel and potent anti-malarial agents.
Brinner KM, Mi Kim J, Habashita H, Gluzman IY, Goldberg DE, Ellman JA. Brinner KM, et al. Among authors: goldberg de. Bioorg Med Chem. 2002 Nov;10(11):3649-61. doi: 10.1016/s0968-0896(02)00207-9. Bioorg Med Chem. 2002. PMID: 12213481
Evaluation of aminohydantoins as a novel class of antimalarial agents.
Meyers MJ, Tortorella MD, Xu J, Qin L, He Z, Lang X, Zeng W, Xu W, Qin L, Prinsen MJ, Sverdrup FM, Eickhoff CS, Griggs DW, Oliva J, Ruminski PG, Jacobsen EJ, Campbell MA, Wood DC, Goldberg DE, Liu X, Lu Y, Lu X, Tu Z, Lu X, Ding K, Chen X. Meyers MJ, et al. Among authors: goldberg de. ACS Med Chem Lett. 2013 Dec 6;5(1):89-93. doi: 10.1021/ml400412x. eCollection 2014 Jan 9. ACS Med Chem Lett. 2013. PMID: 24900778 Free PMC article.
Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents.
Meyers MJ, Anderson EJ, McNitt SA, Krenning TM, Singh M, Xu J, Zeng W, Qin L, Xu W, Zhao S, Qin L, Eickhoff CS, Oliva J, Campbell MA, Arnett SD, Prinsen MJ, Griggs DW, Ruminski PG, Goldberg DE, Ding K, Liu X, Tu Z, Tortorella MD, Sverdrup FM, Chen X. Meyers MJ, et al. Among authors: goldberg de. Bioorg Med Chem. 2015 Aug 15;23(16):5144-50. doi: 10.1016/j.bmc.2015.02.050. Epub 2015 Mar 4. Bioorg Med Chem. 2015. PMID: 25797165 Free PMC article.
Development of piperazine-based hydroxamic acid inhibitors against falcilysin, an essential malarial protease.
Chance JP, Fejzic H, Hernandez O, Istvan ES, Andaya A, Maslov N, Aispuro R, Crisanto T, Nguyen H, Vidal B, Serrano W, Kuwahara B, Pugne Andanado C, Goldberg DE, Mallari JP. Chance JP, et al. Among authors: goldberg de. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1846-1848. doi: 10.1016/j.bmcl.2018.04.010. Epub 2018 Apr 19. Bioorg Med Chem Lett. 2018. PMID: 29691139
273 results