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Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX.
Wang L, Xie L, Ramachandran S, Lee Y, Yan Z, Zhou L, Krajewski K, Liu F, Zhu C, Chen DJ, Strahl BD, Jin J, Dokholyan NV, Chen X. Wang L, et al. Among authors: dokholyan nv. Chem Biol. 2015 Jul 23;22(7):849-61. doi: 10.1016/j.chembiol.2015.05.014. Epub 2015 Jun 25. Chem Biol. 2015. PMID: 26119999 Free PMC article.
Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies.
Zhu C, Dukhovlinova E, Council O, Ping L, Faison EM, Prabhu SS, Potter EL, Upton SL, Yin G, Fay JM, Kincer LP, Spielvogel E, Campbell SL, Benhabbour SR, Ke H, Swanstrom R, Dokholyan NV. Zhu C, et al. Among authors: dokholyan nv. Nat Commun. 2019 Feb 27;10(1):948. doi: 10.1038/s41467-019-08876-w. Nat Commun. 2019. PMID: 30814513 Free PMC article.
p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.
Cloer EW, Siesser PF, Cousins EM, Goldfarb D, Mowrey DD, Harrison JS, Weir SJ, Dokholyan NV, Major MB. Cloer EW, et al. Among authors: dokholyan nv. Mol Cell Biol. 2018 Oct 29;38(22):e00644-17. doi: 10.1128/MCB.00644-17. Print 2018 Nov 15. Mol Cell Biol. 2018. PMID: 30126895 Free PMC article.
MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.
Jiang Y, Zhang Y, Leung JY, Fan C, Popov KI, Su S, Qian J, Wang X, Holtzhausen A, Ubil E, Xiang Y, Davis I, Dokholyan NV, Wu G, Perou CM, Kim WY, Earp HS, Liu P. Jiang Y, et al. Among authors: dokholyan nv. Nat Commun. 2019 Apr 3;10(1):1515. doi: 10.1038/s41467-019-09233-7. Nat Commun. 2019. PMID: 30944303 Free PMC article.
338 results