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A noncanonical function of cGAMP in inflammasome priming and activation.
Swanson KV, Junkins RD, Kurkjian CJ, Holley-Guthrie E, Pendse AA, El Morabiti R, Petrucelli A, Barber GN, Benedict CA, Ting JP. Swanson KV, et al. J Exp Med. 2017 Dec 4;214(12):3611-3626. doi: 10.1084/jem.20171749. Epub 2017 Oct 13. J Exp Med. 2017. PMID: 29030458 Free PMC article.
A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination.
Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. Junkins RD, et al. J Control Release. 2018 Jan 28;270:1-13. doi: 10.1016/j.jconrel.2017.11.030. Epub 2017 Nov 21. J Control Release. 2018. PMID: 29170142 Free PMC article.
Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists.
Collier MA, Junkins RD, Gallovic MD, Johnson BM, Johnson MM, Macintyre AN, Sempowski GD, Bachelder EM, Ting JP, Ainslie KM. Collier MA, et al. Mol Pharm. 2018 Nov 5;15(11):4933-4946. doi: 10.1021/acs.molpharmaceut.8b00579. Epub 2018 Oct 15. Mol Pharm. 2018. PMID: 30281314 Free PMC article.
A spike in inflammation.
Johnson BM, Junkins RD, Ting JP. Johnson BM, et al. Nat Nanotechnol. 2018 Nov;13(11):980-981. doi: 10.1038/s41565-018-0292-y. Nat Nanotechnol. 2018. PMID: 30374158 No abstract available.
STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways.
Johnson BM, Uchimura T, Gallovic MD, Thamilarasan M, Chou WC, Gibson SA, Deng M, Tam JW, Batty CJ, Williams J, Matsushima GK, Bachelder EM, Ainslie KM, Markovic-Plese S, Ting JP. Johnson BM, et al. J Immunol. 2021 May 1;206(9):2015-2028. doi: 10.4049/jimmunol.2001317. Epub 2021 Apr 5. J Immunol. 2021. PMID: 33820855 Free PMC article.
322 results