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The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse.
Lesinski GB, Anghelina M, Zimmerer J, Bakalakos T, Badgwell B, Parihar R, Hu Y, Becknell B, Abood G, Chaudhury AR, Magro C, Durbin J, Carson WE 3rd. Lesinski GB, et al. J Clin Invest. 2003 Jul;112(2):170-80. doi: 10.1172/JCI16603. J Clin Invest. 2003. PMID: 12865406 Free PMC article.
Phase I study of the sequential combination of interleukin-12 and interferon alfa-2b in advanced cancer: evidence for modulation of interferon signaling pathways by interleukin-12.
Eisenbeis CF, Lesinski GB, Anghelina M, Parihar R, Valentino D, Liu J, Nadella P, Sundaram P, Young DC, Sznol M, Walker MJ, Carson WE 3rd. Eisenbeis CF, et al. Among authors: lesinski gb. J Clin Oncol. 2005 Dec 1;23(34):8835-44. doi: 10.1200/JCO.2005.02.1691. J Clin Oncol. 2005. PMID: 16314644 Clinical Trial.
140 results