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Combined effect of Vacc-4x, recombinant human granulocyte macrophage colony-stimulating factor vaccination, and romidepsin on the HIV-1 reservoir (REDUC): a single-arm, phase 1B/2A trial.
Leth S, Schleimann MH, Nissen SK, Højen JF, Olesen R, Graversen ME, Jørgensen S, Kjær AS, Denton PW, Mørk A, Sommerfelt MA, Krogsgaard K, Østergaard L, Rasmussen TA, Tolstrup M, Søgaard OS. Leth S, et al. Among authors: hojen jf. Lancet HIV. 2016 Oct;3(10):e463-72. doi: 10.1016/S2352-3018(16)30055-8. Epub 2016 Jul 7. Lancet HIV. 2016. PMID: 27658863 Clinical Trial.
Short-Course Toll-Like Receptor 9 Agonist Treatment Impacts Innate Immunity and Plasma Viremia in Individuals With Human Immunodeficiency Virus Infection.
Vibholm L, Schleimann MH, Højen JF, Benfield T, Offersen R, Rasmussen K, Olesen R, Dige A, Agnholt J, Grau J, Buzon M, Wittig B, Lichterfeld M, Petersen AM, Deng X, Abdel-Mohsen M, Pillai SK, Rutsaert S, Trypsteen W, De Spiegelaere W, Vandekerchove L, Østergaard L, Rasmussen TA, Denton PW, Tolstrup M, Søgaard OS. Vibholm L, et al. Among authors: hojen jf. Clin Infect Dis. 2017 Jun 15;64(12):1686-1695. doi: 10.1093/cid/cix201. Clin Infect Dis. 2017. PMID: 28329286 Free PMC article. Clinical Trial.
Sequential Vacc-4x and romidepsin during combination antiretroviral therapy (cART): Immune responses to Vacc-4x regions on p24 and changes in HIV reservoirs.
Tapia G, Højen JF, Ökvist M, Olesen R, Leth S, Nissen SK, VanBelzen DJ, O'Doherty U, Mørk A, Krogsgaard K, Søgaard OS, Østergaard L, Tolstrup M, Pantaleo G, Sommerfelt MA. Tapia G, et al. Among authors: hojen jf. J Infect. 2017 Dec;75(6):555-571. doi: 10.1016/j.jinf.2017.09.004. Epub 2017 Sep 14. J Infect. 2017. PMID: 28917661 Clinical Trial.
Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses.
Brinkmann CR, Højen JF, Rasmussen TA, Kjær AS, Olesen R, Denton PW, Østergaard L, Ouyang Z, Lichterfeld M, Yu X, Søgaard OS, Dinarello C, Tolstrup M. Brinkmann CR, et al. Among authors: hojen jf. mSphere. 2018 Feb 14;3(1):e00616-17. doi: 10.1128/mSphere.00616-17. eCollection 2018 Jan-Feb. mSphere. 2018. PMID: 29468194 Free PMC article.
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
Højen JF, Kristensen MLV, McKee AS, Wade MT, Azam T, Lunding LP, de Graaf DM, Swartzwelter BJ, Wegmann M, Tolstrup M, Beckman K, Fujita M, Fischer S, Dinarello CA. Højen JF, et al. Nat Immunol. 2019 Sep;20(9):1138-1149. doi: 10.1038/s41590-019-0467-1. Epub 2019 Aug 19. Nat Immunol. 2019. PMID: 31427775 Free PMC article.
The Use of Toll-Like Receptor Agonists in HIV-1 Cure Strategies.
Martinsen JT, Gunst JD, Højen JF, Tolstrup M, Søgaard OS. Martinsen JT, et al. Among authors: hojen jf. Front Immunol. 2020 Jun 11;11:1112. doi: 10.3389/fimmu.2020.01112. eCollection 2020. Front Immunol. 2020. PMID: 32595636 Free PMC article. Review.
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