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Page 1
Histone deacetylase inhibitor romidepsin inhibits de novo HIV-1 infections.
Jønsson KL, Tolstrup M, Vad-Nielsen J, Kjær K, Laustsen A, Andersen MN, Rasmussen TA, Søgaard OS, Østergaard L, Denton PW, Jakobsen MR. Jønsson KL, et al. Antimicrob Agents Chemother. 2015 Jul;59(7):3984-94. doi: 10.1128/AAC.00574-15. Epub 2015 Apr 20. Antimicrob Agents Chemother. 2015. PMID: 25896701 Free PMC article.
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.
Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR. Jønsson KL, et al. Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391. Nat Commun. 2017. PMID: 28186168 Free PMC article.
cGAS is activated by DNA in a length-dependent manner.
Luecke S, Holleufer A, Christensen MH, Jønsson KL, Boni GA, Sørensen LK, Johannsen M, Jakobsen MR, Hartmann R, Paludan SR. Luecke S, et al. Among authors: jonsson kl. EMBO Rep. 2017 Oct;18(10):1707-1715. doi: 10.15252/embr.201744017. Epub 2017 Aug 10. EMBO Rep. 2017. PMID: 28801534 Free PMC article.
STING dependent sensing - Does HIV actually care?
Krapp C, Jønsson K, Jakobsen MR. Krapp C, et al. Cytokine Growth Factor Rev. 2018 Apr;40:68-76. doi: 10.1016/j.cytogfr.2018.03.002. Epub 2018 Mar 9. Cytokine Growth Factor Rev. 2018. PMID: 29548644 Review.
Cellular Requirements for Sensing and Elimination of Incoming HSV-1 DNA and Capsids.
Sun C, Luecke S, Bodda C, Jønsson KL, Cai Y, Zhang BC, Jensen SB, Nordentoft I, Jensen JM, Jakobsen MR, Paludan SR. Sun C, et al. Among authors: jonsson kl. J Interferon Cytokine Res. 2019 Apr;39(4):191-204. doi: 10.1089/jir.2018.0141. Epub 2019 Mar 11. J Interferon Cytokine Res. 2019. PMID: 30855198
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.
Hotter D, Bosso M, Jønsson KL, Krapp C, Stürzel CM, Das A, Littwitz-Salomon E, Berkhout B, Russ A, Wittmann S, Gramberg T, Zheng Y, Martins LJ, Planelles V, Jakobsen MR, Hahn BH, Dittmer U, Sauter D, Kirchhoff F. Hotter D, et al. Among authors: jonsson kl. Cell Host Microbe. 2019 Jun 12;25(6):858-872.e13. doi: 10.1016/j.chom.2019.05.002. Epub 2019 Jun 4. Cell Host Microbe. 2019. PMID: 31175045 Free PMC article.