Saxena NK - Search Results

1

Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma.

Siddharth S, Muniraj N, Saxena NK, Sharma D. Siddharth S, et al. Among authors: saxena nk. Cancers (Basel). 2019 Mar 30;11(4):453. doi: 10.3390/cancers11040453. Cancers (Basel). 2019. PMID: 30934990 Free PMC article.

2

Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice.

Kuppusamy P, Nagalingam A, Muniraj N, Saxena NK, Sharma D. Kuppusamy P, et al. Among authors: saxena nk. Sci Rep. 2017 Dec 20;7(1):17943. doi: 10.1038/s41598-017-18190-4. Sci Rep. 2017. PMID: 29263422 Free PMC article.

3

ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis.

Chung SJ, Nagaraju GP, Nagalingam A, Muniraj N, Kuppusamy P, Walker A, Woo J, Győrffy B, Gabrielson E, Saxena NK, Sharma D. Chung SJ, et al. Among authors: saxena nk. Autophagy. 2017 Aug 3;13(8):1386-1403. doi: 10.1080/15548627.2017.1332565. Epub 2017 Jul 11. Autophagy. 2017. PMID: 28696138 Free PMC article.

4

Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells.

Muniraj N, Siddharth S, Nagalingam A, Walker A, Woo J, Győrffy B, Gabrielson E, Saxena NK, Sharma D. Muniraj N, et al. Among authors: saxena nk. Carcinogenesis. 2019 Sep 18;40(9):1110-1120. doi: 10.1093/carcin/bgz015. Carcinogenesis. 2019. PMID: 30698683 Free PMC article.

5

Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon honokiol treatment.

Muniraj N, Siddharth S, Shriver M, Nagalingam A, Parida S, Woo J, Elsey J, Gabrielson K, Gabrielson E, Arbiser JL, Saxena NK, Sharma D. Muniraj N, et al. Among authors: saxena nk. Cell Death Discov. 2020 Sep 6;6:81. doi: 10.1038/s41420-020-00315-w. eCollection 2020. Cell Death Discov. 2020. PMID: 32963809 Free PMC article.

6

[No title available]

[No authors listed] [No authors listed] PMID: 34483341

7

Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK/ERK/Stat3 Axis in Hepatocellular Carcinoma.

Siddharth S, Kuppusamy P, Wu Q, Nagalingam A, Saxena NK, Sharma D. Siddharth S, et al. Among authors: saxena nk. Int J Mol Sci. 2022 Jul 22;23(15):8083. doi: 10.3390/ijms23158083. Int J Mol Sci. 2022. PMID: 35897659 Free PMC article.

8

Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.

Nagalingam A, Kuppusamy P, Singh SV, Sharma D, Saxena NK. Nagalingam A, et al. Among authors: saxena nk. Cancer Res. 2014 May 1;74(9):2617-29. doi: 10.1158/0008-5472.CAN-13-2081. Epub 2014 Apr 14. Cancer Res. 2014. PMID: 24732433 Free PMC article.

9

Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes.

Xie B, Nagalingam A, Kuppusamy P, Muniraj N, Langford P, Győrffy B, Saxena NK, Sharma D. Xie B, et al. Among authors: saxena nk. Sci Rep. 2017 Jan 10;7:40070. doi: 10.1038/srep40070. Sci Rep. 2017. PMID: 28071670 Free PMC article.

10

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.

Sengupta S, Nagalingam A, Muniraj N, Bonner MY, Mistriotis P, Afthinos A, Kuppusamy P, Lanoue D, Cho S, Korangath P, Shriver M, Begum A, Merino VF, Huang CY, Arbiser JL, Matsui W, Győrffy B, Konstantopoulos K, Sukumar S, Marignani PA, Saxena NK, Sharma D. Sengupta S, et al. Among authors: saxena nk. Oncogene. 2017 Oct 12;36(41):5709-5721. doi: 10.1038/onc.2017.164. Epub 2017 Jun 5. Oncogene. 2017. PMID: 28581518 Free PMC article.

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