Shah NH - Search Results

1

Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca²⁺ /calmodulin-dependent protein kinase II.

McSpadden ED, Xia Z, Chi CC, Susa AC, Shah NH, Gee CL, Williams ER, Kuriyan J. McSpadden ED, et al. Among authors: shah nh. Protein Sci. 2019 Jun;28(6):1071-1082. doi: 10.1002/pro.3614. Epub 2019 Apr 17. Protein Sci. 2019. PMID: 30942928 Free PMC article.

2

Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.

Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. Visperas PR, et al. Among authors: shah nh. Biochem J. 2015 Jan 1;465(1):149-61. doi: 10.1042/BJ20140793. Biochem J. 2015. PMID: 25287889 Free PMC article.

3

An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor.

Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. Shah NH, et al. Elife. 2016 Oct 4;5:e20105. doi: 10.7554/eLife.20105. Elife. 2016. PMID: 27700984 Free PMC article.

4

Deconstruction of the Ras switching cycle through saturation mutagenesis.

Bandaru P, Shah NH, Bhattacharyya M, Barton JP, Kondo Y, Cofsky JC, Gee CL, Chakraborty AK, Kortemme T, Ranganathan R, Kuriyan J. Bandaru P, et al. Among authors: shah nh. Elife. 2017 Jul 7;6:e27810. doi: 10.7554/eLife.27810. Elife. 2017. PMID: 28686159 Free PMC article.

5

Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen.

Shah NH, Löbel M, Weiss A, Kuriyan J. Shah NH, et al. Elife. 2018 Mar 16;7:e35190. doi: 10.7554/eLife.35190. Elife. 2018. PMID: 29547119 Free PMC article.

6

Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.

Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A. Lo WL, et al. Among authors: shah nh. Nat Immunol. 2018 Jul;19(7):733-741. doi: 10.1038/s41590-018-0131-1. Epub 2018 Jun 18. Nat Immunol. 2018. PMID: 29915297 Free PMC article.

7

Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites.

Cantor AJ, Shah NH, Kuriyan J. Cantor AJ, et al. Among authors: shah nh. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7303-E7312. doi: 10.1073/pnas.1803598115. Epub 2018 Jul 16. Proc Natl Acad Sci U S A. 2018. PMID: 30012625 Free PMC article.

8

The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases.

Shah NH, Amacher JF, Nocka LM, Kuriyan J. Shah NH, et al. Crit Rev Biochem Mol Biol. 2018 Oct;53(5):535-563. doi: 10.1080/10409238.2018.1495173. Epub 2018 Sep 5. Crit Rev Biochem Mol Biol. 2018. PMID: 30183386 Free PMC article. Review.

9

Understanding molecular mechanisms in cell signaling through natural and artificial sequence variation.

Shah NH, Kuriyan J. Shah NH, et al. Nat Struct Mol Biol. 2019 Jan;26(1):25-34. doi: 10.1038/s41594-018-0175-9. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598552 Free PMC article. Review.

10

Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.

Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Lo WL, et al. Among authors: shah nh. Nat Immunol. 2019 Nov;20(11):1481-1493. doi: 10.1038/s41590-019-0502-2. Epub 2019 Oct 14. Nat Immunol. 2019. PMID: 31611699 Free PMC article.

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