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Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells.
Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris M, Adams DL, Hayashi M. Goodspeed A, et al. Among authors: lake j. bioRxiv [Preprint]. 2024 Jun 20:2024.01.18.576251. doi: 10.1101/2024.01.18.576251. bioRxiv. 2024. PMID: 38293103 Free PMC article. Preprint.
Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A. Lake JA, et al. Pediatr Blood Cancer. 2020 Jan;67(1):e28028. doi: 10.1002/pbc.28028. Epub 2019 Oct 8. Pediatr Blood Cancer. 2020. PMID: 31595628 Free PMC article.
Targetable molecular alterations in congenital glioblastoma.
Gilani A, Donson A, Davies KD, Whiteway SL, Lake J, DeSisto J, Hoffman L, Foreman NK, Kleinschmidt-DeMasters BK, Green AL. Gilani A, et al. Among authors: lake j. J Neurooncol. 2020 Jan;146(2):247-252. doi: 10.1007/s11060-019-03377-8. Epub 2019 Dec 24. J Neurooncol. 2020. PMID: 31875306
Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.
Sievers P, Sill M, Schrimpf D, Abdullaev Z, Donson AM, Lake JA, Friedel D, Scheie D, Tynninen O, Rauramaa T, Vepsäläinen KL, Samuel D, Chapman R, Grundy RG, Pajtler KW, Tauziède-Espariat A, Métais A, Varlet P, Snuderl M, Jacques TS, Aldape K, Reuss DE, Korshunov A, Wick W, Pfister SM, von Deimling A, Sahm F, Jones DTW. Sievers P, et al. NPJ Precis Oncol. 2023 Mar 24;7(1):30. doi: 10.1038/s41698-023-00372-1. NPJ Precis Oncol. 2023. PMID: 36964296 Free PMC article.
1,030 results