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Page 1
Modeling Parkinson's disease in midbrain-like organoids.
Smits LM, Reinhardt L, Reinhardt P, Glatza M, Monzel AS, Stanslowsky N, Rosato-Siri MD, Zanon A, Antony PM, Bellmann J, Nicklas SM, Hemmer K, Qing X, Berger E, Kalmbach N, Ehrlich M, Bolognin S, Hicks AA, Wegner F, Sterneckert JL, Schwamborn JC. Smits LM, et al. NPJ Parkinsons Dis. 2019 Apr 5;5:5. doi: 10.1038/s41531-019-0078-4. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 30963107 Free PMC article.
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells.
Monzel AS, Smits LM, Hemmer K, Hachi S, Moreno EL, van Wuellen T, Jarazo J, Walter J, Brüggemann I, Boussaad I, Berger E, Fleming RMT, Bolognin S, Schwamborn JC. Monzel AS, et al. Among authors: smits lm. Stem Cell Reports. 2017 May 9;8(5):1144-1154. doi: 10.1016/j.stemcr.2017.03.010. Epub 2017 Apr 13. Stem Cell Reports. 2017. PMID: 28416282 Free PMC article.
Machine learning-assisted neurotoxicity prediction in human midbrain organoids.
Monzel AS, Hemmer K, Kaoma T, Smits LM, Bolognin S, Lucarelli P, Rosety I, Zagare A, Antony P, Nickels SL, Krueger R, Azuaje F, Schwamborn JC. Monzel AS, et al. Among authors: smits lm. Parkinsonism Relat Disord. 2020 Jun;75:105-109. doi: 10.1016/j.parkreldis.2020.05.011. Epub 2020 May 8. Parkinsonism Relat Disord. 2020. PMID: 32534431 Free article.
Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment.
Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabaté-Soler S, Rosety I, Griesbeck A, Skwirblies F, Zaffaroni G, Smits LM, Su J, Arias-Fuenzalida J, Walter J, Gomez-Giro G, Monzel AS, Qing X, Vitali A, Cruciani G, Boussaad I, Brunelli F, Jäger C, Rakovic A, Li W, Yuan L, Berger E, Arena G, Bolognin S, Schmidt R, Schröder C, Antony PMA, Klein C, Krüger R, Seibler P, Schwamborn JC. Jarazo J, et al. Among authors: smits lm. Mov Disord. 2022 Jan;37(1):80-94. doi: 10.1002/mds.28810. Epub 2021 Oct 12. Mov Disord. 2022. PMID: 34637165 Free PMC article.
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Walter J, Bolognin S, Poovathingal SK, Magni S, Gérard D, Antony PMA, Nickels SL, Salamanca L, Berger E, Smits LM, Grzyb K, Perfeito R, Hoel F, Qing X, Ohnmacht J, Bertacchi M, Jarazo J, Ignac T, Monzel AS, Gonzalez-Cano L, Krüger R, Sauter T, Studer M, de Almeida LP, Tronstad KJ, Sinkkonen L, Skupin A, Schwamborn JC. Walter J, et al. Among authors: smits lm. Cell Rep. 2021 Oct 19;37(3):109864. doi: 10.1016/j.celrep.2021.109864. Cell Rep. 2021. PMID: 34686322 Free article.
Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson's disease modelling and drug screening.
Zanetti C , Spitz S , Berger E , Bolognin S , Smits LM , Crepaz P , Rothbauer M , Rosser JM , Marchetti-Deschmann M , Schwamborn JC , Ertl P . Zanetti C , et al. Among authors: smits lm. Analyst. 2021 Apr 7;146(7):2358-2367. doi: 10.1039/d0an02206c. Epub 2021 Feb 24. Analyst. 2021. PMID: 33625407
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.
Jan A, Jansonius B, Delaidelli A, Bhanshali F, An YA, Ferreira N, Smits LM, Negri GL, Schwamborn JC, Jensen PH, Mackenzie IR, Taubert S, Sorensen PH. Jan A, et al. Among authors: smits lm. Acta Neuropathol Commun. 2018 Jul 2;6(1):54. doi: 10.1186/s40478-018-0554-9. Acta Neuropathol Commun. 2018. PMID: 29961428 Free PMC article.
21 results