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Targeted antibody and cytokine cancer immunotherapies through collagen affinity.
Ishihara J, Ishihara A, Sasaki K, Lee SS, Williford JM, Yasui M, Abe H, Potin L, Hosseinchi P, Fukunaga K, Raczy MM, Gray LT, Mansurov A, Katsumata K, Fukayama M, Kron SJ, Swartz MA, Hubbell JA. Ishihara J, et al. Among authors: potin l. Sci Transl Med. 2019 Apr 10;11(487):eaau3259. doi: 10.1126/scitranslmed.aau3259. Sci Transl Med. 2019. PMID: 30971453 Free PMC article.
Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.
Fankhauser M, Broggi MAS, Potin L, Bordry N, Jeanbart L, Lund AW, Da Costa E, Hauert S, Rincon-Restrepo M, Tremblay C, Cabello E, Homicsko K, Michielin O, Hanahan D, Speiser DE, Swartz MA. Fankhauser M, et al. Among authors: potin l. Sci Transl Med. 2017 Sep 13;9(407):eaal4712. doi: 10.1126/scitranslmed.aal4712. Sci Transl Med. 2017. PMID: 28904226 Clinical Trial.
Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours.
Mansurov A, Ishihara J, Hosseinchi P, Potin L, Marchell TM, Ishihara A, Williford JM, Alpar AT, Raczy MM, Gray LT, Swartz MA, Hubbell JA. Mansurov A, et al. Among authors: potin l. Nat Biomed Eng. 2020 May;4(5):531-543. doi: 10.1038/s41551-020-0549-2. Epub 2020 Apr 13. Nat Biomed Eng. 2020. PMID: 32284554 Free PMC article.
14 results