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Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells.
Coch C, Hommertgen B, Zillinger T, Daßler-Plenker J, Putschli B, Nastaly M, Kümmerer BM, Scheunemann JF, Schumak B, Specht S, Schlee M, Barchet W, Hoerauf A, Bartok E, Hartmann G. Coch C, et al. Among authors: barchet w. Front Immunol. 2019 Mar 27;10:371. doi: 10.3389/fimmu.2019.00371. eCollection 2019. Front Immunol. 2019. PMID: 30972055 Free PMC article.
RNA recognition via TLR7 and TLR8.
Hornung V, Barchet W, Schlee M, Hartmann G. Hornung V, et al. Among authors: barchet w. Handb Exp Pharmacol. 2008;(183):71-86. doi: 10.1007/978-3-540-72167-3_4. Handb Exp Pharmacol. 2008. PMID: 18071655 Review.
Approaching the RNA ligand for RIG-I?
Schlee M, Hartmann E, Coch C, Wimmenauer V, Janke M, Barchet W, Hartmann G. Schlee M, et al. Among authors: barchet w. Immunol Rev. 2009 Jan;227(1):66-74. doi: 10.1111/j.1600-065X.2008.00724.x. Immunol Rev. 2009. PMID: 19120476 Review.
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O, Akira S, Tuschl T, Latz E, Ludwig J, Hartmann G. Schlee M, et al. Among authors: barchet w. Immunity. 2009 Jul 17;31(1):25-34. doi: 10.1016/j.immuni.2009.05.008. Epub 2009 Jul 2. Immunity. 2009. PMID: 19576794 Free PMC article.
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J. Poeck H, et al. Among authors: barchet w. Nat Immunol. 2010 Jan;11(1):63-9. doi: 10.1038/ni.1824. Epub 2009 Nov 15. Nat Immunol. 2010. PMID: 19915568
80 results