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Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, and 5-fluorouracil.
Sekido M, Fujita KI, Kubota Y, Ishida H, Takahashi T, Ohkuma R, Tsunoda T, Ishikawa F, Shibanuma M, Sasaki Y. Sekido M, et al. Among authors: sasaki y. Cancer Chemother Pharmacol. 2019 Jun;83(6):1127-1135. doi: 10.1007/s00280-019-03837-y. Epub 2019 Apr 9. Cancer Chemother Pharmacol. 2019. PMID: 30972456
Pharmacokinetics of capecitabine (Xeloda) in Japanese and Caucasian patients with breast cancer.
Reigner B, Watanabe T, Schüller J, Lucraft H, Sasaki Y, Bridgewater J, Saeki T, McAleer J, Kuranami M, Poole C, Kimura M, Monkhouse J, Yorulmaz C, Weidekamm E, Grange S. Reigner B, et al. Among authors: sasaki y. Cancer Chemother Pharmacol. 2003 Sep;52(3):193-201. doi: 10.1007/s00280-003-0642-8. Epub 2003 May 29. Cancer Chemother Pharmacol. 2003. PMID: 12783206 Clinical Trial.
Gefitinib (Iressa) inhibits the CYP3A4-mediated formation of 7-ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin but activates that of 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]carbonyloxycamptothecin from irinotecan.
Fujita K, Ando Y, Narabayashi M, Miya T, Nagashima F, Yamamoto W, Kodama K, Araki K, Endo H, Sasaki Y. Fujita K, et al. Among authors: sasaki y. Drug Metab Dispos. 2005 Dec;33(12):1785-90. doi: 10.1124/dmd.105.006205. Epub 2005 Aug 25. Drug Metab Dispos. 2005. PMID: 16123050
Novel single nucleotide polymorphism of UGT1A7 gene in Japanese.
Fujita K, Ando Y, Nagashima F, Yamamoto W, Endo H, Kodama K, Araki K, Miya T, Narabayashi M, Sasaki Y. Fujita K, et al. Among authors: sasaki y. Drug Metab Pharmacokinet. 2006 Feb;21(1):75-8. doi: 10.2133/dmpk.21.75. Drug Metab Pharmacokinet. 2006. PMID: 16547397 Free article.
Novel single nucleotide polymorphism of UGT1A9 gene in Japanese.
Fujita K, Ando Y, Nagashima F, Yamamoto W, Endo H, Kodama K, Araki K, Miya T, Narabayashi M, Sasaki Y. Fujita K, et al. Among authors: sasaki y. Drug Metab Pharmacokinet. 2006 Feb;21(1):79-81. doi: 10.2133/dmpk.21.79. Drug Metab Pharmacokinet. 2006. PMID: 16547398 Free article.
6,145 results