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Page 1
Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size.
Rosenbloom DIS, Bacchetti P, Stone M, Deng X, Bosch RJ, Richman DD, Siliciano JD, Mellors JW, Deeks SG, Ptak RG, Hoh R, Keating SM, Dimapasoc M, Massanella M, Lai J, Sobolewski MD, Kulpa DA, Busch MP; Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group. Rosenbloom DIS, et al. Among authors: kulpa da. PLoS Comput Biol. 2019 Apr 12;15(4):e1006849. doi: 10.1371/journal.pcbi.1006849. eCollection 2019 Apr. PLoS Comput Biol. 2019. PMID: 30978183 Free PMC article.
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.
Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, Sékaly RP, Chomont N. Procopio FA, et al. Among authors: kulpa da. EBioMedicine. 2015 Jun 27;2(8):874-83. doi: 10.1016/j.ebiom.2015.06.019. eCollection 2015 Aug. EBioMedicine. 2015. PMID: 26425694 Free PMC article.
Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Gavegnano C, Brehm JH, Dupuy FP, Talla A, Ribeiro SP, Kulpa DA, Cameron C, Santos S, Hurwitz SJ, Marconi VC, Routy JP, Sabbagh L, Schinazi RF, Sékaly RP. Gavegnano C, et al. Among authors: kulpa da. PLoS Pathog. 2017 Dec 21;13(12):e1006740. doi: 10.1371/journal.ppat.1006740. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29267399 Free PMC article.
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.
Wonderlich ER, Subramanian K, Cox B, Wiegand A, Lackman-Smith C, Bale MJ, Stone M, Hoh R, Kearney MF, Maldarelli F, Deeks SG, Busch MP, Ptak RG, Kulpa DA. Wonderlich ER, et al. Among authors: kulpa da. PLoS Pathog. 2019 Oct 14;15(10):e1008074. doi: 10.1371/journal.ppat.1008074. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31609991 Free PMC article.
CD8+ lymphocytes do not impact SIV reservoir establishment under ART.
Statzu M, Jin W, Fray EJ, Wong AKH, Kumar MR, Ferrer E, Docken SS, Pinkevych M, McBrien JB, Fennessey CM, Keele BF, Liang S, Harper JL, Mutascio S, Franchitti L, Wang H, Cicetti D, Bosinger SE, Carnathan DG, Vanderford TH, Margolis DM, Garcia-Martinez JV, Chahroudi A, Paiardini M, Siliciano J, Davenport MP, Kulpa DA, Siliciano RS, Silvestri G. Statzu M, et al. Among authors: kulpa da. Nat Microbiol. 2023 Feb;8(2):299-308. doi: 10.1038/s41564-022-01311-9. Epub 2023 Jan 23. Nat Microbiol. 2023. PMID: 36690860 Free PMC article.
Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary.
Sanders-Beer BE, Archin NM, Brumme ZL, Busch MP, Deleage C, O'Doherty U, Hughes SH, Jerome KR, Jones RB, Karn J, Kearney MF, Keele BF, Kulpa DA, Laird GM, Li JZ, Lichterfeld MD, Nussenzweig MC, Persaud D, Yukl SA, Siliciano RF, Mellors JW. Sanders-Beer BE, et al. Among authors: kulpa da. AIDS Res Hum Retroviruses. 2023 Jun 19. doi: 10.1089/AID.2022.0188. Online ahead of print. AIDS Res Hum Retroviruses. 2023. PMID: 37126090
Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays.
Kuzmichev YV, Lackman-Smith C, Bakkour S, Wiegand A, Bale MJ, Musick A, Bernstein W, Aronson N, Ake J, Tovanabutra S, Stone M, Ptak RG, Kearney MF, Busch MP, Wonderlich ER, Kulpa DA. Kuzmichev YV, et al. Among authors: kulpa da. Sci Rep. 2023 Jul 6;13(1):10958. doi: 10.1038/s41598-023-37223-9. Sci Rep. 2023. PMID: 37414788 Free PMC article.
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G. McBrien JB, et al. Among authors: kulpa da. Nature. 2020 Feb;578(7793):154-159. doi: 10.1038/s41586-020-1946-0. Epub 2020 Jan 22. Nature. 2020. PMID: 31969705 Free PMC article.
42 results