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Page 1
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Perez-Ruiz E, Minute L, Otano I, Alvarez M, Ochoa MC, Belsue V, de Andrea C, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Llacer C, Alvarez M, de Luque V, Molina C, Teijeira A, Berraondo P, Melero I. Perez-Ruiz E, et al. Among authors: melero i. Nature. 2019 May;569(7756):428-432. doi: 10.1038/s41586-019-1162-y. Epub 2019 May 1. Nature. 2019. PMID: 31043740 Free article.
Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.
Tirapu I, Huarte E, Guiducci C, Arina A, Zaratiegui M, Murillo O, Gonzalez A, Berasain C, Berraondo P, Fortes P, Prieto J, Colombo MP, Chen L, Melero I. Tirapu I, et al. Among authors: melero i. Cancer Res. 2006 Feb 15;66(4):2442-50. doi: 10.1158/0008-5472.CAN-05-1681. Cancer Res. 2006. PMID: 16489051 Free article.
Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.
Huarte E, Larrea E, Hernández-Alcoceba R, Alfaro C, Murillo O, Arina A, Tirapu I, Azpilicueta A, Hervás-Stubbs S, Bortolanza S, Pérez-Gracia JL, Civeira MP, Prieto J, Riezu-Boj JI, Melero I. Huarte E, et al. Among authors: melero i. Mol Ther. 2006 Jul;14(1):129-38. doi: 10.1016/j.ymthe.2006.02.015. Epub 2006 Apr 19. Mol Ther. 2006. PMID: 16627004 Free article.
[The immunotherapy potential of agonistic anti-CD137 (4-1BB) monoclonal antibodies for malignancies and chronic viral diseases].
Alfaro C, Murillo O, Tirapu I, Azpilicueta A, Huarte E, Arina A, Arribillaga L, Pérez-Gracia JL, Bendandi M, Prieto J, Lasarte JJ, Melero I. Alfaro C, et al. Among authors: melero i. An Sist Sanit Navar. 2006 Jan-Apr;29(1):77-96. doi: 10.4321/s1137-66272006000100007. An Sist Sanit Navar. 2006. PMID: 16670731 Free article. Review. Spanish.
The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma.
Arina A, Murillo O, Hervás-Stubbs S, Azpilikueta A, Dubrot J, Tirapu I, Huarte E, Alfaro C, Pérez-Gracia JL, González-Aseguinolaza G, Sarobe P, Lasarte JJ, Jamieson A, Prieto J, Raulet DH, Melero I. Arina A, et al. Among authors: melero i. Int J Cancer. 2007 Sep 15;121(6):1282-95. doi: 10.1002/ijc.22795. Int J Cancer. 2007. PMID: 17520674 Free article.
Immunotherapy and immunoescape in colorectal cancer.
Mazzolini G, Murillo O, Atorrasagasti C, Dubrot J, Tirapu I, Rizzo M, Arina A, Alfaro C, Azpilicueta A, Berasain C, Perez-Gracia JL, Gonzalez A, Melero I. Mazzolini G, et al. Among authors: melero i. World J Gastroenterol. 2007 Nov 28;13(44):5822-31. doi: 10.3748/wjg.v13.i44.5822. World J Gastroenterol. 2007. PMID: 17990348 Free PMC article. Review.
372 results