Mackay GM - Search Results

1

Stratification of cancer and diabetes based on circulating levels of formate and glucose.

Pietzke M, Arroyo SF, Sumpton D, Mackay GM, Martin-Castillo B, Camps J, Joven J, Menendez JA, Vazquez A; METTEN study group. Pietzke M, et al. Among authors: mackay gm. Cancer Metab. 2019 Apr 24;7:3. doi: 10.1186/s40170-019-0195-x. eCollection 2019. Cancer Metab. 2019. PMID: 31049200 Free PMC article.

2

Quantification of folate metabolism using transient metabolic flux analysis.

Tedeschi PM, Johnson-Farley N, Lin H, Shelton LM, Ooga T, Mackay G, Van Den Broek N, Bertino JR, Vazquez A. Tedeschi PM, et al. Cancer Metab. 2015 May 28;3:6. doi: 10.1186/s40170-015-0132-6. eCollection 2015. Cancer Metab. 2015. PMID: 26023330 Free PMC article.

3

Serine one-carbon catabolism with formate overflow.

Meiser J, Tumanov S, Maddocks O, Labuschagne CF, Athineos D, Van Den Broek N, Mackay GM, Gottlieb E, Blyth K, Vousden K, Kamphorst JJ, Vazquez A. Meiser J, et al. Among authors: mackay gm. Sci Adv. 2016 Oct 28;2(10):e1601273. doi: 10.1126/sciadv.1601273. eCollection 2016 Oct. Sci Adv. 2016. PMID: 27819051 Free PMC article.

4

Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells.

Dolfi SC, Medina DJ, Kareddula A, Paratala B, Rose A, Dhami J, Chen S, Ganesan S, Mackay G, Vazquez A, Hirshfield KM. Dolfi SC, et al. Oncotarget. 2017 Jul 4;8(27):44639-44653. doi: 10.18632/oncotarget.17961. Oncotarget. 2017. PMID: 28591718 Free PMC article.

5

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells.

Dornier E, Rabas N, Mitchell L, Novo D, Dhayade S, Marco S, Mackay G, Sumpton D, Pallares M, Nixon C, Blyth K, Macpherson IR, Rainero E, Norman JC. Dornier E, et al. Nat Commun. 2017 Dec 21;8(1):2255. doi: 10.1038/s41467-017-02101-2. Nat Commun. 2017. PMID: 29269878 Free PMC article.

6

Increased formate overflow is a hallmark of oxidative cancer.

Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton JP, Dornier E, Sumpton D, Mackay GM, Blyth K, Patel KJ, Niclou SP, Vazquez A. Meiser J, et al. Among authors: mackay gm. Nat Commun. 2018 Apr 10;9(1):1368. doi: 10.1038/s41467-018-03777-w. Nat Commun. 2018. PMID: 29636461 Free PMC article.

7

Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth.

Rath N, Munro J, Cutiongco MF, Jagiełło A, Gadegaard N, McGarry L, Unbekandt M, Michalopoulou E, Kamphorst JJ, Sumpton D, Mackay G, Vennin C, Pajic M, Timpson P, Olson MF. Rath N, et al. Cancer Res. 2018 Jun 15;78(12):3321-3336. doi: 10.1158/0008-5472.CAN-17-1339. Epub 2018 Apr 18. Cancer Res. 2018. PMID: 29669760 Free PMC article.

8

Improving the metabolic fidelity of cancer models with a physiological cell culture medium.

Vande Voorde J, Ackermann T, Pfetzer N, Sumpton D, Mackay G, Kalna G, Nixon C, Blyth K, Gottlieb E, Tardito S. Vande Voorde J, et al. Sci Adv. 2019 Jan 2;5(1):eaau7314. doi: 10.1126/sciadv.aau7314. eCollection 2019 Jan. Sci Adv. 2019. PMID: 30613774 Free PMC article.

9

Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response.

McGregor GH, Campbell AD, Fey SK, Tumanov S, Sumpton D, Blanco GR, Mackay G, Nixon C, Vazquez A, Sansom OJ, Kamphorst JJ. McGregor GH, et al. Cancer Res. 2020 Jan 15;80(2):175-188. doi: 10.1158/0008-5472.CAN-19-0644. Epub 2019 Sep 27. Cancer Res. 2020. PMID: 31562248 Free article.

10

Formate induces a metabolic switch in nucleotide and energy metabolism.

Oizel K, Tait-Mulder J, Fernandez-de-Cossio-Diaz J, Pietzke M, Brunton H, Lilla S, Dhayade S, Athineos D, Blanco GR, Sumpton D, Mackay GM, Blyth K, Zanivan SR, Meiser J, Vazquez A. Oizel K, et al. Among authors: mackay gm. Cell Death Dis. 2020 May 4;11(5):310. doi: 10.1038/s41419-020-2523-z. Cell Death Dis. 2020. PMID: 32366892 Free PMC article.

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