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2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease.
Davidson J, Molitor E, Moores S, Gale SE, Subramanian K, Jiang X, Sidhu R, Kell P, Zhang J, Fujiwara H, Davidson C, Helquist P, Melancon BJ, Grigalunas M, Liu G, Salahi F, Wiest O, Xu X, Porter FD, Pipalia NH, Cruz DL, Holson EB, Schaffer JE, Walkley SU, Maxfield FR, Ory DS. Davidson J, et al. Among authors: liu g. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1545-1561. doi: 10.1016/j.bbalip.2019.04.011. Epub 2019 Apr 30. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31051283 Free PMC article.
Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts.
Cruz DL, Pipalia N, Mao S, Gadi D, Liu G, Grigalunas M, O'Neill M, Quinn TR, Kipper A, Ekebergh A, Dimmling A, Gartner C, Melancon BJ, Wagner FF, Holson E, Helquist P, Wiest O, Maxfield FR. Cruz DL, et al. Among authors: liu g. ACS Pharmacol Transl Sci. 2021 May 27;4(3):1136-1148. doi: 10.1021/acsptsci.1c00033. eCollection 2021 Jun 11. ACS Pharmacol Transl Sci. 2021. PMID: 34151204 Free PMC article.
Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic.
Work EM, Ferraudi G, Kiefer L, Liu G, Grigalunas M, Bhardwaj A, Kaur R, Dempsey JM, Wüstner D, Helquist P, Wiest O. Work EM, et al. Among authors: liu g. J Org Chem. 2021 Jan 15;86(2):1612-1621. doi: 10.1021/acs.joc.0c02460. Epub 2020 Dec 28. J Org Chem. 2021. PMID: 33369429 Free PMC article.
Prognostic impact and reasons for variability by tumor location in gastric cancer.
Huang YX, He HY, Chen K, Liu HD, Zu D, Liang C, Bao QM, Hu YC, Liu GX, Zhong YK, Zhang CK, Deng MC, He YH, Jing J, Shi Y, Xu SF, Teng YS, Ye Z, Cheng XD. Huang YX, et al. Among authors: liu gx. World J Gastroenterol. 2024 Nov 28;30(44):4709-4724. doi: 10.3748/wjg.v30.i44.4709. World J Gastroenterol. 2024. PMID: 39610778 Free PMC article.
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