Williams DP - Search Results

1

Acute Metabolic Switch Assay Using Glucose/Galactose Medium in HepaRG Cells to Detect Mitochondrial Toxicity.

Kamalian L, Douglas O, Jolly CE, Snoeys J, Simic D, Monshouwer M, Williams DP, Park BK, Chadwick AE. Kamalian L, et al. Among authors: williams dp. Curr Protoc Toxicol. 2019 Jun;80(1):e76. doi: 10.1002/cptx.76. Epub 2019 May 6. Curr Protoc Toxicol. 2019. PMID: 31058461

2

Metabolism and bioactivation of clozapine by human liver in vitro.

Pirmohamed M, Williams D, Madden S, Templeton E, Park BK. Pirmohamed M, et al. J Pharmacol Exp Ther. 1995 Mar;272(3):984-90. J Pharmacol Exp Ther. 1995. PMID: 7891353

3

The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man.

Maggs JL, Williams D, Pirmohamed M, Park BK. Maggs JL, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1463-75. J Pharmacol Exp Ther. 1995. PMID: 8531117

4

Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency.

Pirmohamed M, Williams D, Tingle MD, Barry M, Khoo SH, O'Mahony C, Wilkins EG, Breckenridge AM, Park BK. Pirmohamed M, et al. AIDS. 1996 May;10(5):501-7. doi: 10.1097/00002030-199605000-00008. AIDS. 1996. PMID: 8724041

5

Characterisation of the toxic metabolite(s) of naphthalene.

Wilson AS, Davis CD, Williams DP, Buckpitt AR, Pirmohamed M, Park BK. Wilson AS, et al. Among authors: williams dp. Toxicology. 1996 Dec 18;114(3):233-42. doi: 10.1016/s0300-483x(96)03515-9. Toxicology. 1996. PMID: 8980712

6

Disposition of amodiaquine and related antimalarial agents in human neutrophils: implications for drug design.

Naisbitt DJ, Ruscoe JE, Williams D, O'Neill PM, Pirmohamed M, Park BK. Naisbitt DJ, et al. J Pharmacol Exp Ther. 1997 Feb;280(2):884-93. J Pharmacol Exp Ther. 1997. PMID: 9023303

7

Bioactivation and inactivation of aflatoxin B1 by human, mouse and rat liver preparations: effect on SCE in human mononuclear leucocytes.

Wilson AS, Williams DP, Davis CD, Tingle MD, Park BK. Wilson AS, et al. Among authors: williams dp. Mutat Res. 1997 Feb 3;373(2):257-64. doi: 10.1016/s0027-5107(96)00205-9. Mutat Res. 1997. PMID: 9042408

8

Neutrophil cytotoxicity of the chemically reactive metabolite(s) of clozapine: possible role in agranulocytosis.

Williams DP, Pirmohamed M, Naisbitt DJ, Maggs JL, Park BK. Williams DP, et al. J Pharmacol Exp Ther. 1997 Dec;283(3):1375-82. J Pharmacol Exp Ther. 1997. PMID: 9400013

9

Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs.

Naisbitt DJ, Williams DP, O'Neill PM, Maggs JL, Willock DJ, Pirmohamed M, Park BK. Naisbitt DJ, et al. Among authors: williams dp. Chem Res Toxicol. 1998 Dec;11(12):1586-95. doi: 10.1021/tx980148k. Chem Res Toxicol. 1998. PMID: 9860505

10

Induction of metabolism-dependent and -independent neutrophil apoptosis by clozapine.

Williams DP, Pirmohamed M, Naisbitt DJ, Uetrecht JP, Park BK. Williams DP, et al. Mol Pharmacol. 2000 Jul;58(1):207-16. doi: 10.1124/mol.58.1.207. Mol Pharmacol. 2000. PMID: 10860943

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