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Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses.
Phillips MJ, Wallace KA, Dickerson SJ, Miller MJ, Verhoeven AD, Martin JM, Wright LS, Shen W, Capowski EE, Percin EF, Perez ET, Zhong X, Canto-Soler MV, Gamm DM. Phillips MJ, et al. Among authors: capowski ee. Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):2007-19. doi: 10.1167/iovs.11-9313. Invest Ophthalmol Vis Sci. 2012. PMID: 22410558 Free PMC article.
iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration.
Singh R, Shen W, Kuai D, Martin JM, Guo X, Smith MA, Perez ET, Phillips MJ, Simonett JM, Wallace KA, Verhoeven AD, Capowski EE, Zhang X, Yin Y, Halbach PJ, Fishman GA, Wright LS, Pattnaik BR, Gamm DM. Singh R, et al. Among authors: capowski ee. Hum Mol Genet. 2013 Feb 1;22(3):593-607. doi: 10.1093/hmg/dds469. Epub 2012 Nov 8. Hum Mol Genet. 2013. PMID: 23139242 Free PMC article.
Functional analysis of serially expanded human iPS cell-derived RPE cultures.
Singh R, Phillips MJ, Kuai D, Meyer J, Martin JM, Smith MA, Perez ET, Shen W, Wallace KA, Capowski EE, Wright LS, Gamm DM. Singh R, et al. Among authors: capowski ee. Invest Ophthalmol Vis Sci. 2013 Oct 17;54(10):6767-78. doi: 10.1167/iovs.13-11943. Invest Ophthalmol Vis Sci. 2013. PMID: 24030465 Free PMC article.
Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2.
Phillips MJ, Perez ET, Martin JM, Reshel ST, Wallace KA, Capowski EE, Singh R, Wright LS, Clark EM, Barney PM, Stewart R, Dickerson SJ, Miller MJ, Percin EF, Thomson JA, Gamm DM. Phillips MJ, et al. Among authors: capowski ee. Stem Cells. 2014 Jun;32(6):1480-92. doi: 10.1002/stem.1667. Stem Cells. 2014. PMID: 24532057 Free PMC article.
Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.
Capowski EE, Simonett JM, Clark EM, Wright LS, Howden SE, Wallace KA, Petelinsek AM, Pinilla I, Phillips MJ, Meyer JS, Schneider BL, Thomson JA, Gamm DM. Capowski EE, et al. Hum Mol Genet. 2014 Dec 1;23(23):6332-44. doi: 10.1093/hmg/ddu351. Epub 2014 Jul 9. Hum Mol Genet. 2014. PMID: 25008112 Free PMC article.
36 results