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Synergistic drug combination effectively blocks Ebola virus infection.
Sun W, He S, Martínez-Romero C, Kouznetsova J, Tawa G, Xu M, Shinn P, Fisher E, Long Y, Motabar O, Yang S, Sanderson PE, Williamson PR, García-Sastre A, Qiu X, Zheng W. Sun W, et al. Among authors: tawa g. Antiviral Res. 2017 Jan;137:165-172. doi: 10.1016/j.antiviral.2016.11.017. Epub 2016 Nov 24. Antiviral Res. 2017. PMID: 27890675 Free PMC article.
Repurposing a novel parathyroid hormone analogue to treat hypoparathyroidism.
Krishnan V, Ma YL, Chen CZ, Thorne N, Bullock H, Tawa G, Javella-Cauley C, Chu S, Li W, Kohn W, Adrian MD, Benson C, Liu L, Sato M, Zheng W, Pilon AM, Yang NN, Bryant HU. Krishnan V, et al. Among authors: tawa g. Br J Pharmacol. 2018 Jan;175(2):262-271. doi: 10.1111/bph.14028. Epub 2017 Nov 28. Br J Pharmacol. 2018. PMID: 28898923 Free PMC article.
Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.
Capuzzi SJ, Sun W, Muratov EN, Martínez-Romero C, He S, Zhu W, Li H, Tawa G, Fisher EG, Xu M, Shinn P, Qiu X, García-Sastre A, Zheng W, Tropsha A. Capuzzi SJ, et al. Among authors: tawa g. J Med Chem. 2018 Apr 26;61(8):3582-3594. doi: 10.1021/acs.jmedchem.8b00035. Epub 2018 Apr 17. J Med Chem. 2018. PMID: 29624387 Free PMC article.
Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIβ).
Krishnan K, Ziniel P, Li H, Huang X, Hupalo D, Gombakomba N, Guerrero SM, Dotrang T, Lu X, Caridha D, Sternberg AR, Hughes E, Sun W, Bargieri DY, Roepe PD, Sciotti RJ, Wilkerson MD, Dalgard CL, Tawa GJ, Wang AQ, Xu X, Zheng W, Sanderson PE, Huang W, Williamson KC. Krishnan K, et al. ACS Pharmacol Transl Sci. 2020 Sep 11;3(5):948-964. doi: 10.1021/acsptsci.0c00078. eCollection 2020 Oct 9. ACS Pharmacol Transl Sci. 2020. PMID: 33073193 Free PMC article.
54 results